Essential hypertension is a complex multifactorial disease process that involves the
interaction of multiple genes at various loci throughout the genome, and the influence of …

The relationship between acrolein (CH2= CH‐CHO) and brain infarction is the focus of this
review. It has been found that acrolein is produced mainly within cells from polyamines by …

Background and Purpose—We found previously that plasma levels of acrolein (CH2=
CHCHO) and spermine oxidase (SMO) were well correlated with the degree of severity of …

Cytochrome c release from mitochondria to the cytosol represents a critical step in
apoptosis, correlated to the activation of the caspase cascade. In this report, we show that …

Exposure of experimental animals to increased angiotensin II (ANG II) induces hypertension
associated with cardiac hypertrophy, inflammation, and myocardial necrosis and fibrosis …

The natural polyamines spermine, spermidine and putrescine, polycationic molecules at
physiological pH, interact with mitochondrial membranes at two specific binding sites …

Polyamines (putrescine, spermidine and spermine) are essential for cell growth and
differentiation. Nitric oxide exhibits antihypertrophic functions and inhibits cardiac …

Although the amount of research on copper amine oxidases has grown rapidly and
substantially in the past decade, the field unfortunately suffers from lack of cohesion and …

Urea transporters have been cloned from kidney medulla (UT-A) and erythrocytes (UT-B).
We determined whether UT-A proteins could be detected in heart and whether their …

We studied the role of perivascular adipose tissue (PVAT) in the control of vascular function
in an in vivo experimental model of hypertension produced by angiotensin II infusion by …