Depression in neurodegenerative diseases: Common mechanisms and current treatment options

CPC Galts, LEB Bettio, DC Jewett, CC Yang… - Neuroscience & …, 2019 - Elsevier
Major depressive disorder (MDD) is a highly prevalent psychiatric disorder and a major
cause of disability worldwide. This neurological condition is commonly associated with …

Neuropsychiatric burden in Huntington's disease

RA Paoli, A Botturi, A Ciammola, V Silani, C Prunas… - Brain sciences, 2017 - mdpi.com
Huntington's disease is a disorder that results in motor, cognitive, and psychiatric problems.
The symptoms often take different forms and the presence of disturbances of the psychic …

[图书][B] Huntington's disease

G Bates, S Tabrizi, L Jones - 2014 - books.google.com
This fourth edition of Huntington's Disease presents a comprehensive summary of the
current knowledge of this disease, including the major scientific and clinical advances that …

Huntington disease: a quarter century of progress since the gene discovery

CM Testa, J Jankovic - Journal of the neurological sciences, 2019 - Elsevier
Huntington disease (HD) is an autosomal dominant neurodegenerative disorder
characterized by motor, behavioral, and cognitive manifestations. It is caused by an …

Cognitive and behavioral changes in Huntington disease before diagnosis

JS Paulsen, AC Miller, T Hayes, E Shaw - Handbook of clinical neurology, 2017 - Elsevier
Phenotypic manifestations of Huntington disease (HD) can be detected at least 15 years
prior to the time when a motor diagnosis is given. Advances in clinical care and future …

Huntington's disease

AD Ha, VSC Fung - Current opinion in neurology, 2012 - journals.lww.com
With predictive testing allowing the identification of gene-positive individuals prior to disease
onset, the prodromal stage of Huntington's disease provides an ideal period for the use of …

Suicidal ideation and behavior in Huntington's disease: Systematic review and recommendations

ZR Kachian, S Cohen-Zimerman, D Bega… - Journal of affective …, 2019 - Elsevier
Background An increased risk of suicide in Huntington's disease (HD) patients is well
documented, with rates significantly higher than those of the general population as well as …

Characterization of the Huntington intermediate CAG repeat expansion phenotype in PHAROS

A Killoran, KM Biglan, J Jankovic, S Eberly, E Kayson… - Neurology, 2013 - AAN Enterprises
Objectives: We aimed to describe the clinical phenotype conferred by the intermediate-
length huntingtin allele CAG repeat expansion in a population-based study. Methods: The …

[HTML][HTML] Suicidal ideation in a European Huntington's disease population

AAM Hubers, E Van Duijn, RAC Roos… - Journal of affective …, 2013 - Elsevier
Background Previous studies indicate increased prevalences of suicidal ideation, suicide
attempts, and completed suicide in Huntington's disease (HD) compared with the general …

Psychological interventions for people with Huntington's disease: a call to arms

N Zarotti, M Dale, F Eccles… - Journal of Huntington's …, 2020 - content.iospress.com
Background: Although Huntington's disease (HD) can cause a wide range of psychological
difficulties, no review has ever been carried out on the range of psychological interventions …