Exposure to environmental organic pollutants has triggered significant ecological impacts
and adverse health outcomes, which have been received substantial and increasing …

Drug discovery is adapting to novel technologies such as data science, informatics, and
artificial intelligence (AI) to accelerate effective treatment development while reducing costs …

Target discovery is one of the essential steps in modern drug development, and the
identification of promising targets is fundamental for developing first-in-class drug. A variety …

Abstract The IUPHAR/BPS Guide to PHARMACOLOGY (GtoPdb; https://www.
guidetopharmacology. org) is an open-access, expert-curated, online database that …

Large-language models (LLMs) such as GPT-4 caught the interest of many scientists.
Recent studies suggested that these models could be useful in chemistry and materials …

Abstract LIPID MAPS (LIPID Metabolites and Pathways Strategy), www. lipidmaps. org,
provides a systematic and standardized approach to organizing lipid structural and …

Antibody-drug conjugates (ADCs) are a class of innovative biopharmaceutical drugs, which,
via their antibody (mAb) component, deliver and release their potent warhead (aka. payload) …

Increasing production and use of chemicals and awareness of their impact on ecosystems
and humans has led to large interest for broadening the knowledge on the chemical status …

Arachidonic and adrenic acids in the membrane play key roles in ferroptosis. Here, we
reveal that lipoprotein-associated phospholipase A2 (Lp-PLA2) controls intracellular …

Per-and polyfluoroalkyl substances (PFAS) are of high concern, with calls to regulate them
as a class. In 2021, the Organisation for Economic Co-operation and Development (OECD) …