[HTML][HTML] Extracellular vesicles in nanomedicine and regenerative medicine: A review over the last decade
Small extracellular vesicles (sEVs) are known to be secreted by a vast majority of cells.
These sEVs, specifically exosomes, induce specific cell-to-cell interactions and can activate …
These sEVs, specifically exosomes, induce specific cell-to-cell interactions and can activate …
[HTML][HTML] Engineered Extracellular Vesicles: Emerging Therapeutic Strategies for Translational Applications
JN Ziegler, C Tian - International Journal of Molecular Sciences, 2023 - mdpi.com
Extracellular vesicles (EVs) are small, membrane-bound vesicles used by cells to deliver
biological cargo such as proteins, mRNA, and other biomolecules from one cell to another …
biological cargo such as proteins, mRNA, and other biomolecules from one cell to another …
Immunogenic bifunctional nanoparticle suppresses programmed cell death-ligand 1 in cancer and dendritic cells to enhance adaptive immunity and chemo …
Blockade of programmed cell death-1/programmed cell death-ligand 1 (PD-L1) immune
checkpoints with monoclonal antibodies has shown great promise for cancer treatment, but …
checkpoints with monoclonal antibodies has shown great promise for cancer treatment, but …
Leveraging efferocytosis blockade for improved cancer chemo-immunotherapy through synchronized release of doxorubicin and BMS777607 confined within tailored …
Effective antitumor activity of chemotherapy can be counterbalanced by efferocytosis by
generating immunosuppressive tumor microenvironment. Targeted blocking efferocytosis at …
generating immunosuppressive tumor microenvironment. Targeted blocking efferocytosis at …
An electrochemical biosensor designed with entropy-driven autocatalytic DNA circuits for sensitive detection of ovarian cancer-derived exosomes
Y Deng, T Zhou, K Hu, Y Peng, X Jia, J Yang… - Biosensors and …, 2024 - Elsevier
Intelligent artificial DNA circuits have emerged as a promising approach for modulating
signaling pathways and signal transduction through rational design, which may contribute to …
signaling pathways and signal transduction through rational design, which may contribute to …
Early‐Responsive Immunoregulation Therapy Improved Microenvironment for Bone Regeneration Via Engineered Extracellular Vesicles
T Lu, Y Liu, X Huang, S Sun, H Xu, A Jin… - Advanced …, 2024 - Wiley Online Library
Overactivated inflammatory reactions hinder the bone regeneration process. Timely
transformation of microenvironment from pro‐inflammatory to anti‐inflammatory after acute …
transformation of microenvironment from pro‐inflammatory to anti‐inflammatory after acute …
M1 macrophage-derived exosome for reprograming M2 macrophages and combining endogenous NO gas therapy with enhanced photodynamic synergistic therapy …
RY Zhang, K Cheng, ZY Huang, XS Zhang, Y Li… - Journal of Colloid and …, 2024 - Elsevier
Reprogramming immunosuppressive M2 macrophages into M1 macrophages in tumor site
provides a new strategy for the immunotherapy of colorectal cancer. In this study, M1 …
provides a new strategy for the immunotherapy of colorectal cancer. In this study, M1 …
The role of extracellular vesicles in the treatment of prostate cancer
C Hu, Q Chen, T Wu, X Du, Y Dong, Z Peng, W Xue… - Small, 2024 - Wiley Online Library
Prostate cancer (PCa) has become a public health concern in elderly men due to an ever‐
increasing number of estimated cases. Unfortunately, the available treatments are …
increasing number of estimated cases. Unfortunately, the available treatments are …
Hierarchical Self‐Assembly Molecular Building Blocks as Intelligent Nanoplatforms for Ovarian Cancer Theranostics
S Li, Q Chen, Q Xu, Z Wei, Y Shen, H Wang… - Advanced …, 2024 - Wiley Online Library
Hierarchical self‐assembly from simple building blocks to complex polymers is a feasible
approach to constructing multi‐functional smart materials. However, the polymerization …
approach to constructing multi‐functional smart materials. However, the polymerization …
The study of designing a controlled drug release using oxaliplatin-loaded hydrogel for ovarian cancer treatment
JV Lim, MR Nepacina, YC Hsu - Journal of the Taiwan Institute of Chemical …, 2024 - Elsevier
Background Ovarian cancer is the most lethal gynecological cancer due to its high
recurrence rate. Oxaliplatin is partially cross-resistant with platinum drugs to enhance the …
recurrence rate. Oxaliplatin is partially cross-resistant with platinum drugs to enhance the …