When mycophenolic acid (MPA) was originally marketed for immunosuppressive therapy,
fixed doses were recommended by the manufacturer. Awareness of the potential for a more …

Hematocrit-related issues remain a major barrier for (regulatory) acceptance of the classical
dried blood spot (DBS) analysis in the bioanalytical and clinical field. Lately, many attempts …

Dried blood spots (DBS) have been used in newborn screening programs for several years.
More recently, there has been growing interest in using DBS as a home sampling tool for the …

Dosage adjustment of anti-epileptic drugs by therapeutic drug monitoring (TDM) is very
useful, especially for the first-generation anti-epileptic drugs (AEDs). Microsampling—the …

Dried blood spot (DBS) has been used for more than 50 years for the screening of inborn
errors of metabolism in newborns. Although DBS has remained the standard approach for …

The hematocrit (Hct) effect is one of the most important hurdles currently preventing more
widespread implementation of quantitative dried blood spot (DBS) analysis in a routine …

Newborn screening (NBS) programs operate in many countries, processing millions of dried
bloodspot (DBS) samples annually. In addition to early identification of various adverse …

Therapeutic drug monitoring (TDM) is an important tool for correlating the administered drug
dose to drug and metabolite concentrations in the body and to therapeutic and adverse …

Therapeutic drug monitoring (TDM) of tyrosine kinase inhibitors (TKIs) is not yet performed
routinely in the standard care of oncology patients, although it offers a high potential to …

Background: Microsampling techniques have several advantages over traditional blood
collection. Dried blood spot (DBS) sampling and blood collection with heparinized …