Human risk associated with palytoxin exposure

JR Deeds, MD Schwartz - Toxicon, 2010 - Elsevier
Palytoxin (PTX) was first isolated from the zoanthid Palythoa toxica. Evaluation of PTX
toxicity using various animal models determined that PTX was extremely potent through …

Palytoxin acts through Na+, K+-ATPase

E Habermann - Toxicon, 1989 - Elsevier
E. Habermann. Palytoxin acts through Na+, K+-ATPase. Toxicon27, 1171–1187, 1989.—
Palytoxin is the most potent animal toxin, with a unique structure. The author's group has …

Palytoxin toxicology: animal studies

R Munday - Toxicon, 2011 - Elsevier
Palytoxin and its derivatives have been implicated in toxic events in humans following
ingestion or inhalation, and many studies on the toxicities of these substances to animals …

[图书][B] Inhalation toxicology

H Salem, SA Katz - 2014 - books.google.com
The lungs provide a significant opportunity for the introduction of both therapeutic and toxic
chemicals into the human body. In occupational and domestic environments, hazardous …

Palytoxin induces K+ efflux from yeast cells expressing the mammalian sodium pump.

G Scheiner-Bobis, DM zu Heringdorf, M Christ… - Molecular …, 1994 - ASPET
Palytoxin causes potassium efflux and sodium influx in all investigated animals cells. Much
evidence points to the sodium pump (Na+/K (+)-ATPase) as the target of the toxin. A …

Specific and dynamic detection of palytoxins by in vitro microplate assay with human neuroblastoma cells

B Espiña, E Cagide, MC Louzao… - Bioscience …, 2009 - portlandpress.com
Palytoxin is one of the most complex and biggest molecules known to show extreme acute
toxicity. The dinoflagellate Ostreopsis spp., the producer organism of palytoxin, has been …

Palytoxin. Recent electrophysiological and pharmacological evidence for several mechanisms of action.

C Frelin, C Van Renterghem - General pharmacology, 1995 - europepmc.org
1. Palytoxin is one of the most potent toxins known so far. It acts as an haemolysin and alters
the functioning of excitable cells. 2. A primary action of palytoxin in excitable cells is to …

The cytolytic and cytotoxic activities of palytoxin

M Bellocci, GL Sala, S Prandi - Toxicon, 2011 - Elsevier
Palytoxin (PlTX) is one of the largest compound present in nature and, with its strong ability
to modify the normal function of different biological systems, is also classified as one of the …

Therapy and prophylaxis of inhaled biological toxins

BM Paddle - Journal of Applied Toxicology, 2003 - Wiley Online Library
This review highlights the current lack of therapeutic and prophylactic treatments for use
against inhaled biological toxins, especially those considered as potential biological warfare …

HEMOLYTIC ACTIVITY OF HETEROCAPSA CIRCULARISQUAMA (DINOPHYCEAE) AND ITS POSSIBLE INVOLVEMENT IN SHELLFISH TOXICITY

T Oda, Y Sato, D Kim, T Muramatsu… - Journal of …, 2001 - Wiley Online Library
Heterocapsa circularisquama Horiguchi is lethal to shellfish, particularly bivalves such as
pearl oysters (Pinctada fucata Gould). No detrimental effects of this flagellate on fish have …