Microglia are the predominant immune cells of the central nervous system (CNS) that exert
key physiological roles required for maintaining CNS homeostasis, notably in response to …

Disturbances in the sleep–wake cycle and circadian rhythms are common symptoms of
Alzheimer Disease (AD), and they have generally been considered as late consequences of …

The proliferation and activation of microglial cells is a hallmark of several neurodegenerative
conditions. This mechanism is regulated by the activation of the colony-stimulating factor 1 …

Recent years have witnessed a revolution in our understanding of microglia biology,
including their major role in the etiology and pathogenesis of neurodegenerative diseases …

Over the past few decades, research on Alzheimer's disease (AD) has focused on
pathomechanisms linked to two of the major pathological hallmarks of extracellular …

Stress is critically involved in the development and progression of disease. From the stress
of undergoing treatments to facing your own mortality, the physiological processes that …

Alzheimer's disease (AD) involves progressive accumulation of amyloid β-peptide (Aβ) and
neurofibrillary pathologies, and glucose hypometabolism in brain regions critical for …

Alzheimer's disease (AD) is an age‐related neurodegenerative disorder characterized by
aggregation of toxic forms of amyloid β peptide (Aβ). Treatment strategies have largely been …

Altered neurogenesis is suggested to be involved in the onset of brain diseases, including
mental disorders and neurodegenerative diseases. Neurotrophic factors are well known for …

Glucocorticoids serve as key stress response hormones that facilitate stress coping.
However, sustained glucocorticoid exposure is associated with adverse consequences on …