[HTML][HTML] New, improved treatments for Chagas disease: from the R&D pipeline to the patients

I Ribeiro, AM Sevcsik, F Alves, G Diap… - PLoS neglected …, 2009 - journals.plos.org
Endemic throughout Latin America with a prevalence rate of approximately 1.4%, Chagas
disease (CD) is estimated to kill 14,000 people every year, which is more people in the …

Trypanosomatid parasites causing neglected diseases

K Nussbaum, J Honek, CC Cadmus… - Current medicinal …, 2010 - ingentaconnect.com
Parasitic diseases such as Kala azar (visceral leishmaniasis), Chagas disease (American
trypanosomiasis) and African sleeping sickness (human African trypanosomiasis) are …

Geographic distribution of Chagas disease vectors in Brazil based on ecological niche modeling

R Gurgel-Gonçalves, C Galvao, J Costa… - Journal of tropical …, 2012 - Wiley Online Library
Although Brazil was declared free from Chagas disease transmission by the domestic vector
Triatoma infestans, human acute cases are still being registered based on transmission by …

[HTML][HTML] Enteric neuronal damage, intramuscular denervation and smooth muscle phenotype changes as mechanisms of chagasic megacolon: evidence from a long …

CF Campos, SD Cangussú, ALC Duz, CT Cartelle… - PLoS …, 2016 - journals.plos.org
We developed a novel murine model of long-term infection with Trypanosoma cruzi with the
aim to elucidate the pathogenesis of megacolon and the associated adaptive and …

Evolution of Chagas' disease in Brazil. Epidemiological perspective and challenges for the future: a critical review

R Bello Corassa, C Aceijas… - … in Public Health, 2017 - journals.sagepub.com
Aims: This article aimed to provide a critical review of the evolution of Chagas' disease
(ChD) in Brazil, its magnitude, historical development and management, and challenges for …

[HTML][HTML] Triatoma williami in intradomiciliary environments of urban areas in Mato Grosso State, Brazil: domiciliation process of a wild species?

MF Martins, SC de Moraes, J Oliveira… - Infectious Diseases of …, 2022 - Springer
Abstract Background Triatomines in Latin America are natural Chagas disease (ChD)
vectors. Triatomine domiciliation is one of the main factors increasing the occurrence risk of …

[HTML][HTML] Profile of the Trypanosoma cruzi vector infestation in Jaboticatubas, State of Minas Gerais, Brazil

CJ Belisário, JVL Dias, L Diotaiuti - Revista da Sociedade Brasileira …, 2013 - SciELO Brasil
Introduction This work aimed to analyze the triatomine infestation scenario in Jaboticatubas
after 30 years of the uninterrupted actions of the Program of Chagas Disease Control …

[PDF][PDF] Estudo do megacólon chagásico em modelo murino com ênfase nas alterações morfológicas da parede intestinal

ALC Duz - pgbiologiacelular.icb.ufmg.br
RESUMO O estudo da doença de Chagas experimental é um modelo de potencial
importância para o entendimento da patogênese do megaesôfago e do megacólon. Vários …

Estudo da expressão gênica em pacientes com doença de Chagas recebendo tratamento com Benznidazole: a procura por um biomarcador de cura

N Gaburo Junior - 2020 - teses.usp.br
Mais de 100 anos após a doença de Chagas (DC) ter sido descrita pela primeira vez, em
alguns países, como o Brasil, o benznidazole (BZN) é o único medicamento disponível para …

[PDF][PDF] Middlesex University Research Repository

R Bello-Corassa, C Aceijas, P Brito Alves, H Garelick - academia.edu
Aims: This paper aimed to provide a critical review of the evolution of Chagas' disease in
Brazil, its magnitude, historical development and management, and challenges for the …