CircRNAs, covalently closed noncoding RNAs, are widely expressed in a wide range of
species ranging from viruses to plants to mammals. CircRNAs were enriched in the Wnt …

Cancer is one of the leading causes of human death worldwide. Treatment of cancer
exhausts significant medical resources, and the morbidity and mortality caused by cancer is …

Reversible, spatial, and temporal regulation of metabolic reprogramming and epigenetic
homeostasis are prominent hallmarks of carcinogenesis. Cancer cells reprogram their …

Lung cancer (LC) is a heterogeneous disease with high malignant degree, rapid growth,
and early metastasis. The clinical outcomes of LC patients are generally poor due to the …

Triple-negative breast cancer (TNBC) is the most challenging breast cancer subtype for its
high rates of relapse, great metastatic potential, and short overall survival. How cancer cells …

A potential reason for the failure of tumor therapies is treatment resistance. Resistance to
chemotherapy, radiotherapy, and immunotherapy continues to be a major obstacle in clinic …

Exosomes, extracellular vesicles with a diameter of 40 to 160 nm, are among the smallest
extracellular vesicles released by cells. They deliver different cargoes, including proteins …

Long non-coding RNAs (lncRNAs) are a class of RNA transcripts more than 200 nucleotides
in length that play crucial roles in cancer development and progression. With the rapid …

Fatty acid metabolism, particularly fatty acid synthesis, is a very important cellular
physiological process in which nutrients are used for energy storage and biofilm synthesis …

Cancer drug resistance remains a formidable challenge in modern oncology, necessitating
innovative therapeutic strategies. The convergence of intricate regulatory networks involving …