Cannabis (Cannabis sativa L.) plants from the family Cannabidaceae have been used since
ancient times, to produce fibers, oil, and for medicinal purposes. Psychoactive delta-9 …

The rapid increase of obesity and associated diseases has become a major global health
problem. Adipose tissues are critical for whole-body homeostasis. The gut microbiota has …

Background Bioactive lipids produced by human cells or by the gut microbiota might play an
important role in health and disease. Dietary intakes are key determinants of the gut …

Peroxisome proliferator-activated receptors (PPARs) are a family of nuclear receptors
including PPARα, PPARγ, and PPARβ/δ, acting as transcription factors to regulate the …

Food intake regulation in humans is a complex process controlled by the dynamic
interaction of homeostatic and hedonic systems. Homeostatic regulation is controlled by …

Ulcerative colitis (UC) is a chronic autoimmune disorder affecting the colonic mucosa. UC is
a subtype of inflammatory bowel disease along with Crohn's disease and presents with …

The management of visceral pain in patients with disorders of gut–brain interaction, notably
irritable bowel syndrome, presents a considerable clinical challenge, with few available …

Obesity has reached epidemic proportion worldwide and in all ages. Available evidence
points to a multifactorial pathogenesis involving gene predisposition and environmental …

The endocannabinoid (EC) system has pleiotropic functions in the body. It plays a key role in
energy homeostasis and the development of metabolic disorders being a mediator in the …

The maintenance of intestinal homeostasis is fundamentally important to health. Intestinal
barrier function and immune regulation are key determinants of intestinal homeostasis and …