This research work aimed to prepare and optimize “self-nanoemulsifying drug delivery
system (SNEDDS)” by applying full factorial design (FFD) to improve solubilization and …

Natural substances have been the principal source of medications since antiquity. Natural
goods are gaining popularity as a source of novel medications. This article investigates a …

Background: The oral route is a highly recommended route for the delivery of a drug. But
most lipophilic drugs are difficult to deliver via this route due to their low aqueous solubility …

Background: Nanotech products are gaining more attention depending on their advantages
for improving drug solubility, maintenance of drug targeting, and attenuation of drug toxicity …

Lipid based formulations such as self emulsifying drug delivery system (SEDDS) and self
microemulsifying drug delivery systems (SMEDDS) are designed to improve the oral …

Triterpenoids, as a more important and the largest group of phytochemicals, exist in
thousands of medicinal plants from which more than 20,000 substances with up to 100 basic …

目的制备齐墩果酸(OA) 线粒体靶向脂质体(α-TOS-TPP-OA), 以实现药物的靶向性并提高其抗
胰腺癌的活性. 方法通过两步反应, 合成三苯基膦(TPP) 修饰的生育酚琥珀酸酯(α-TOS) …

The liquid self-emulsifying drug delivery system (L-SEDDS), commonly used to deliver
effective but poorly water-soluble oleanolic acid (OA), has many limitations such as high …

The pharmacokinetics and metabolic knowledge of natural medicine (phytochemicals and
herbal formulations) are highly beneficial for clinical dose adjustment and in the …

目的冬凌草甲素水溶性差, 生物半衰期短, 生物利用度低, 制备冬凌草甲素立方液晶纳米粒,
提高其溶解度, 延长药物作用时间. 方法以新型液晶材料植烷三醇, 结合丙二醇-泊洛沙姆407 …