口服给药是一种便利的, 不需要使用针头等其他器械的给药方式. 然而由于中药制剂的胃肠道
消化吸收往往不尽人意, 而导致其口服的生物利用度也较低. 为了能够改善中药制剂的吸收 …

Objective: The aim of this study was to develop and evaluate self microemulsifying drug
delivery system (SMEDDS) to improve oral bioavailability of tacrolimus. Methods: The …

Objective: The objective of this study was to develop, characterize, and conduct
pharmacokinetic and pharmacodynamic studies on ursolic acid solid self microemulsifying …

Abstract Apple, Malus domestica Borkh., a member of Rosaceae family, is one of the most
grown, favored and processed fruit worldwide, generating an immense volume of industrial …

Traditional Chinese medicine (TCM) is a treasure of the traditional culture of the Chinese
nation, although many Chinese medicine ingredients have strong pharmacological effects in …

Quetiapine fumarate is an antipsychotic drug with plasma half-life 6 hr. and having poor oral
bioavailability (9%) because of first pass metabolism. The aim of the present study was to …

In the past few decades, using traditional Chinese medicines (TCMs), including Panax
ginseng as pharmaceutical, nutraceutical, and healthcare products has expanded globally …

Background: Crossbow medicine needle is a traditional external therapy. However,
acupuncture pain, inaccurate administration, secondary infection, and poor patient …

Triterpenoids, as a more important and the largest group of phytochemicals, exist in
thousands of medicinal plants from which more than 20,000 substances with up to 100 basic …

ABSTRACT Cilnidipine, a 2, 4-dihydropyridine antihypertensive, is poorly bioavailable and
belongs to Biopharmaceutical Classification System Class II. The present study was carried …