[HTML][HTML] Focus on sex and gender: what we need to know in the management of rheumatoid arthritis

B Maranini, A Bortoluzzi, E Silvagni… - Journal of personalized …, 2022 - mdpi.com
Rheumatoid arthritis (RA) is a chronic inflammatory disease, affecting mostly women with a
female/male ratio of 3: 1. It is characterized by symmetrical polyarthritis, leading to …

Immunological memory in rheumatic inflammation—a roadblock to tolerance induction

P Maschmeyer, HD Chang, Q Cheng… - Nature Reviews …, 2021 - nature.com
Why do we still have no cure for chronic inflammatory diseases? One reason could be that
current therapies are based on the assumption that chronic inflammation is driven by …

[HTML][HTML] A novel 3D spheroid model of rheumatoid arthritis synovial tissue incorporating fibroblasts, endothelial cells, and macrophages

EML Philippon, LJE van Rooijen, F Khodadust… - Frontiers in …, 2023 - frontiersin.org
Objective Rheumatoid Arthritis (RA) is a progressive and systemic autoimmune disorder
associated with chronic and destructive joint inflammation. The hallmarks of joint synovial …

[HTML][HTML] Nutrition and rheumatoid arthritis onset: a prospective analysis using the UK Biobank

CB Mazzucca, L Scotti, G Cappellano, F Barone-Adesi… - Nutrients, 2022 - mdpi.com
Rheumatoid arthritis (RA) is a chronic inflammatory disease that affects the joints. The
multifactorial etiopathogenesis of RA has been heavily investigated, but is still only partially …

[HTML][HTML] Proteomics of immune cells from liver tumors reveals immunotherapy targets

FP Canale, J Neumann, J von Renesse, E Loggi… - Cell genomics, 2023 - cell.com
Elucidating the mechanisms by which immune cells become dysfunctional in tumors is
critical to developing next-generation immunotherapies. We profiled proteomes of cancer …

Broad proteomic screen reveals shared serum proteomic signature in patients with psoriatic arthritis and psoriasis without arthritis

E Leijten, W Tao, J Pouw, T van Kempen… - …, 2021 - academic.oup.com
Objective To identify novel serum proteins involved in the pathogenesis of PsA as compared
with healthy controls, psoriasis (Pso) and AS, and to explore which proteins best correlated …

Immunometabolism: an emerging target for immunotherapies to treat rheumatoid arthritis

JL Mangal, N Basu, HJJ Wu, AP Acharya - Immunometabolism, 2021 - journals.lww.com
An increasing number of findings highlight the fundamental role of metabolism in
autoimmunity. This growing recognition of metabolic irregularities being a factor of immune …

Negotiating professional tasks in a hospital: A qualitative study of rheumatologists and occupational therapists in the management of hand osteoarthritis

HJ Magnussen, I Kjeken, I Pinxsterhuis… - Journal of …, 2023 - Taylor & Francis
Purpose Societal change and rise in demand for healthcare call for new health professional
practices and task redistribution. Through negotiated order theory, this study explores how …

Biological and synthetic target DMARDs in psoriatic arthritis

E Silvagni, A Bortoluzzi, G Ciancio, M Govoni - Pharmacological Research, 2019 - Elsevier
Psoriatic arthritis (PsA) is a chronic multi-faceted immune-mediated systemic disorder,
characterized by articular, cutaneous, enthesis, nail and spine involvement. Articular …

A versatile, secure, and sustainable all-in-one biobank-registry data solution: The A3BC REDCap model

C Willers, T Lynch, V Chand, M Islam… - Biopreservation and …, 2022 - liebertpub.com
Introduction: A key element in the big data revolution is large-scale biobanking and the
associated development of high-quality data collections and supporting informatics …