[HTML][HTML] Lessons learned from the clinical presentation of common variable immunodeficiency disorders: a systematic review and meta-analysis

LMA Janssen, M van der Flier, E de Vries - Frontiers in immunology, 2021 - frontiersin.org
Background Diagnostic delay in common variable immunodeficiency disorders (CVID) is
considerable. There is no generally accepted symptom-recognition framework for its early …

[HTML][HTML] Gut microbiome and common variable immunodeficiency: few certainties and many outstanding questions

G Varricchi, R Poto, G Ianiro, A Punziano… - Frontiers in …, 2021 - frontiersin.org
Common variable immunodeficiency (CVID) is the most common symptomatic primary
antibody immunodeficiency, characterized by reduced serum levels of IgG, IgA, and/or IgM …

[HTML][HTML] Common variable immunodeficiency-associated cancers: the role of clinical phenotypes, immunological and genetic factors

L Bruns, V Panagiota, S von Hardenberg… - Frontiers in …, 2022 - frontiersin.org
Objective The aim of this study was to investigate the prevalence of cancer and associating
clinical, immunological, and genetic factors in a German cohort of patients with common …

[HTML][HTML] Lack of gut secretory immunoglobulin A in memory B-cell dysfunction-associated disorders: a possible gut-spleen axis

R Carsetti, A Di Sabatino, MM Rosado… - Frontiers in …, 2020 - frontiersin.org
Background: B-1a B cells and gut secretory IgA (SIgA) are absent in asplenic mice. Human
immunoglobulin M (IgM) memory B cells, which are functionally equivalent to mouse B-1a B …

[HTML][HTML] Treatment strategies for GLILD in common variable immunodeficiency: a systematic review

OAC Lamers, BM Smits, HL Leavis, GJ de Bree… - Frontiers in …, 2021 - frontiersin.org
Introduction Besides recurrent infections, a proportion of patients with Common Variable
Immunodeficiency Disorders (CVID) may suffer from immune dysregulation such as …

[HTML][HTML] Heterogeneity of liver disease in common variable immunodeficiency disorders

A Pecoraro, L Crescenzi, G Varricchi… - Frontiers in …, 2020 - frontiersin.org
Common variable immunodeficiency (CVID) is the most frequent primary immunodeficiency
(PID) in adulthood and is characterized by severe reduction of immunoglobulin serum levels …

[HTML][HTML] The pattern of malignancies in Down syndrome and its potential context with the immune system

D Satgé, MG Seidel - Frontiers in Immunology, 2018 - frontiersin.org
The immune surveillance theory of cancer posits that the body's immune system detects and
destroys randomly occurring malignant cells. This theory is based on the observation of the …

[HTML][HTML] Cytokine dysregulation despite immunoglobulin replacement therapy in common variable immunodeficiency (CVID)

R Poto, A Pecoraro, AL Ferrara, A Punziano… - Frontiers in …, 2023 - frontiersin.org
Introduction Common variable immunodeficiency (CVID) is the most prevalent symptomatic
primary immunodeficiency. CVID is a heterogeneous disorder with a presumed multifactorial …

[HTML][HTML] Recent developments on semiconducting polymer nanoparticles as smart photo-therapeutic agents for cancer treatments—A review

NS Rejinold, G Choi, JH Choy - Polymers, 2021 - mdpi.com
Semiconducting polymer nanoparticles (SPN) have been emerging as novel functional nano
materials for phototherapy which includes PTT (photo-thermal therapy), PDT (photodynamic …

Common variable immune deficiency: case studies

C Cunningham-Rundles - Hematology 2014, the American …, 2019 - ashpublications.org
Common variable immune deficiency (CVID) is one of the most common congenital immune
defects encountered in clinical practice. The condition occurs equally in males and females …