The (apparent) antibody paradox in COVID-19

R Ameratunga, ST Woon, E Lea, R Steele… - Expert Review of …, 2022 - Taylor & Francis
Introduction The immunological response to COVID-19 is only partly understood. It is
increasingly clear that the virus triggers an inappropriate host inflammatory reaction in …

The Rapidly Expanding Genetic Spectrum of Common Variable Immunodeficiency–Like Disorders

R Ameratunga, ESJ Edwards, K Lehnert… - The Journal of Allergy …, 2023 - Elsevier
The understanding of common variable immunodeficiency disorders (CVID) is in evolution.
CVID was previously a diagnosis of exclusion. New diagnostic criteria have allowed the …

Common variable immunodeficiency disorders, T-cell responses to SARS-CoV-2 vaccines, and the risk of chronic COVID-19

R Ameratunga, H Longhurst, R Steele, K Lehnert… - The Journal of Allergy …, 2021 - Elsevier
COVID-19 has had a calamitous effect on the global community. Despite intense study, the
immunologic response to the infection is only partially understood. In addition to older age …

Common variable immunodeficiency-associated cancers: the role of clinical phenotypes, immunological and genetic factors

L Bruns, V Panagiota, S von Hardenberg… - Frontiers in …, 2022 - frontiersin.org
Objective The aim of this study was to investigate the prevalence of cancer and associating
clinical, immunological, and genetic factors in a German cohort of patients with common …

Liver disease accompanied by enteropathy in common variable immunodeficiency: Common pathophysiological mechanisms

FMS Lima, M Toledo-Barros, VAF Alves… - Frontiers in …, 2022 - frontiersin.org
Common variable immunodeficiency (CVID) is one of the inborn errors of immunity that have
the greatest clinical impact. Rates of morbidity and mortality are higher in patients with CVID …

Severe COVID-19 is a T cell immune dysregulatory disorder triggered by SARS-CoV-2

R Ameratunga, ST Woon, R Steele… - Expert Review of …, 2022 - Taylor & Francis
Introduction COVID-19 has had a calamitous impact on the global community. Apart from at
least 6 M deaths, hundreds of millions have been infected and a much greater number have …

Perspective: diagnostic laboratories should urgently develop T cell assays for SARS-CoV-2 infection

R Ameratunga, ST Woon, A Jordan… - Expert review of …, 2021 - Taylor & Francis
Introduction: Diagnostic tests play a critical role in the management of Sars-CoV-2, the virus
responsible for COVID-19. There are two groups of tests, which are in widespread use to …

SARS-CoV-2 omicron: Light at the end of the long pandemic tunnel or another false dawn for immunodeficient patients?

R Ameratunga, E Leung, ST Woon, L Chan… - The Journal of Allergy …, 2022 - Elsevier
COVID-19 has had a disastrous impact on the world. Apart from at least 6 million deaths,
countless COVID-19 survivors are suffering long-term physical and psychiatric morbidity …

Bronchiectasis is associated with delayed diagnosis and adverse outcomes in the New Zealand Common Variable Immunodeficiency Disorders cohort study

R Ameratunga, A Jordan, A Cavadino… - Clinical & …, 2021 - academic.oup.com
Common variable immunodeficiency disorders (CVID) are multi-system disorders where
target organ damage is mediated by infective, autoimmune and inflammatory processes …

Incidence, management experience and characteristics of patients with giardiasis and common variable immunodeficiency

I Díaz-Alberola, JF Gutiérrez-Bautista… - Journal of Clinical …, 2022 - mdpi.com
Common variable immunodeficiency (CVID) is an antibody immunodeficiency with a wide
variety of clinical and immunological manifestations, and whose genetic cause is found in …