Discovery of several poorly water soluble drugs in the past decade has led to the constant
need of developing a novel dosage form which increases the solubility of these drug. They …

Ursolic acid is a molecule with several therapeutic applications not yet commercially
explored because of its bioavailability-limiting water insolubility. To avoid this drawback …

Glipizide (GLZ) is an oral hypoglycemic agent, which is a weakly aqueous soluble drug. The
solubility values of GLZ in various neat solvents are scarce in the literature. Hence, the …

In recent years, the formulation of poorly soluble compounds presented interesting
challenges for formulation scientists in the pharmaceutical industry. Up to 40% of new …

Praziquantel (PZQ) is an anthelminthic agent active against parasitic flatworms of the
Schistosoma type and the most important drug for the treatment and morbidity control of …

The aim of the present study was to formulate a non-effervescent floating drug delivery
system of glipizide, a poorly water soluble drug. The solubility of glipizide was initially …

The poor solubility of drug substances in water and their low dissolution rate in aqueous GIT
fluid often leads toinsufficient bioavailability. Glipizide is a class-II antidiabetic drug which is …

Objective: The aim of the present study was to enhance the dissolution of poorly-water
soluble Olmesartan medoxomil by solid dispersion preparation and formation of inclusion …

Solubility is an important physicochemical factor affecting absorption of drug and its
therapeutic effectiveness. Diacerein (DIA) is a poorly water-soluble anti-inflammatory …

The objective of the study is to evaluate the individual main effects and combined (or
interaction) effects of Hydroxy propyl β cyclodextrin (HPβCD), poly vinyl pyrrolidone (PVP …