Noise-induced hearing loss (NIHL) is the second most common cause of sensorineural
hearing loss, after age-related hearing loss, and affects approximately 5% of the world's …

Patterns are ubiquitous in living systems and underlie the dynamic organization of cells,
tissues, and embryos. Mathematical frameworks have been devised to account for the self …

Organoids have certain cellular composition and physiological features in common with real
organs, making them promising models of organ formation, function, and diseases …

Loss of sensory hair cells (HCs) in the mammalian inner ear leads to permanent hearing
and vestibular defects, whereas loss of HCs in zebrafish results in their regeneration. We …

Mammalian hair cells do not functionally regenerate in adulthood but can regenerate at
embryonic and neonatal stages in mice by direct transdifferentiation of neighboring …

Adult mammalian tissues such as heart, brain, retina, and the sensory structures of the inner
ear do not effectively regenerate, although a latent capacity for regeneration exists at …

This study evaluated the size-dependent effects of high-density polyethylene (HDPE)
fragments in zebrafish. Larvae were exposed to HDPE microplastic (MP) in three sizes …

Sensorineural deafness becomes an inevitable worldwide healthy problem, yet the current
curative therapy is limited. Emerging evidences demonstrate mitochondrial dysfunction …

Despite a prevalence greater than cancer or diabetes, there are no currently approved drugs
for the treatment of hearing loss. Research over the past two decades has led to a vastly …

The motor protein myosin-15 is necessary for the development and maintenance of
mechanosensory stereocilia, and mutations in myosin-15 cause hereditary deafness. In …