Mechanisms in endocrinology: pathogenesis of type 2 diabetes in South Asians

LEH Bakker, MA Sleddering… - European journal of …, 2013 - academic.oup.com
The risk of developing type 2 diabetes mellitus (T2DM) is exceptionally high among both
native and migrant South Asians. T2DM occurs more often and at a younger age and lower …

[HTML][HTML] Associations of short stature and components of height with incidence of type 2 diabetes: mediating effects of cardiometabolic risk factors

C Wittenbecher, O Kuxhaus, H Boeing, N Stefan… - Diabetologia, 2019 - Springer
Aims/hypothesis This study aimed to evaluate associations of height as well as components
of height (sitting height and leg length) with risk of type 2 diabetes and to explore to what …

The interplay between sex, ethnicity, and adipose tissue characteristics

K Karastergiou - Current Obesity Reports, 2015 - Springer
The obesity epidemic in the USA affects disproportionately women and the ethnic minorities.
On the other hand, female sex is traditionally associated with a favorable fat distribution …

[HTML][HTML] Evidence that multiple defects in lipid regulation occur before hyperglycemia during the prodrome of type-2 diabetes

SG Anderson, WB Dunn, M Banerjee, M Brown… - PLoS …, 2014 - journals.plos.org
Background Blood-vessel dysfunction arises before overt hyperglycemia in type-2 diabetes
(T2DM). We hypothesised that a metabolomic approach might identify metabolites/pathways …

Longitudinal study of cardiometabolic risk from early adolescence to early adulthood in an ethnically diverse cohort

S Harding, MJ Silva, OR Molaodi, ZE Enayat… - BMJ open, 2016 - bmjopen.bmj.com
Objective To examine influences of adiposity from early adolescence to early 20s on
cardiovascular disease (CVD) risk in the multiethnic Determinants of young Adult Social well …

[HTML][HTML] Obesity and metabolic care of children of South Asian ethnicity in western society

R Sivasubramanian, S Malhotra, AK Fitch, V Singhal - Children, 2021 - mdpi.com
South Asians constitute one-fourth of the world's population and are distributed significantly
in western countries. With exponentially growing numbers, childhood obesity is of global …

Infant body composition and adipokine concentrations in relation to maternal gestational weight gain

AC Estampador, J Pomeroy, F Renström… - Diabetes …, 2014 - Am Diabetes Assoc
OBJECTIVE To investigate associations of maternal gestational weight gain and body
composition and their impact on offspring body composition and adipocytokine, glucose …

[HTML][HTML] Maternal factors in pregnancy and ethnicity influence childhood adiposity, cardiac structure, and function

S Khan, A Whatmore, R Perchard, A Khan… - Frontiers in …, 2022 - frontiersin.org
Importance The links between maternal and offspring adiposity and metabolic status are
well established. There is much less evidence for the impact of these relationships …

Type 2 diabetes in South Asians compared to Europeans: Higher risk and earlier development of major cardiovascular events irrespective of the presence and degree …

J van Niel, PHLM Geelhoed‐Duijvestijn… - Endocrinology …, 2021 - Wiley Online Library
Abstract Introduction South Asians with diabetes have more severe diabetic retinopathy
(DR) and cardiovascular complications than white Caucasians. However, how big this gap is …

Adipocytokine associations with insulin resistance in british South Asians

DR Webb, K Khunti, S Chatterjee… - Journal of Diabetes …, 2013 - Wiley Online Library
Aims. Adipocytokines are implicated in the pathogenesis of type 2 diabetes and may
represent identifiable precursors of metabolic disease within high‐risk groups. We …