[HTML][HTML] Trypanosoma cruzi IV Causing Outbreaks of Acute Chagas Disease and Infections by Different Haplotypes in the Western Brazilian Amazonia

WM Monteiro, LKC Magalhães, ARN de Sá, ML Gomes… - 2012 - journals.plos.org
Background Chagas disease is an emergent tropical disease in the Brazilian Amazon
Region, with an increasing number of cases in recent decades. In this region, the sylvatic …

In vivo susceptibility to benznidazole of Trypanosoma cruzi strains from the western Brazilian Amazon

APM Teston, WM Monteiro, D Reis… - Tropical Medicine & …, 2013 - Wiley Online Library
Objective To assess the susceptibility of T rypanosoma cruzi strains from A mazon to
benznidazole. Methods We studied 23 strains of T. cruzi obtained from humans in the acute …

[HTML][HTML] Trypanosoma cruzi I–III in southern Brazil causing individual and mixed infections in humans, sylvatic reservoirs and triatomines

NG Abolis, SM De Araujo, MJ de Ornelas Toledo… - Acta tropica, 2011 - Elsevier
The aim of this study was to characterise Discrete Typing Units (DTUs) of 28 isolates of
Trypanosoma cruzi from humans (15), triatomines (9), and opossums (4) in the state of …

[HTML][HTML] Coinfection with Different Trypanosoma cruzi Strains Interferes with the Host Immune Response to Infection

CM Rodrigues, HMS Valadares… - PLoS neglected …, 2010 - journals.plos.org
A century after the discovery of Trypanosoma cruzi in a child living in Lassance, Minas
Gerais, Brazil in 1909, many uncertainties remain with respect to factors determining the …

[HTML][HTML] Unequivocal Identification of Subpopulations in Putative Multiclonal Trypanosoma cruzi Strains by FACs Single Cell Sorting and Genotyping

HMS Valadares, JR Pimenta, M Segatto… - PLoS neglected …, 2012 - journals.plos.org
Trypanosoma cruzi, the etiological agent of Chagas disease, is a polymorphic species.
Evidence suggests that the majority of the T. cruzi populations isolated from afflicted …

Differential parasitological, molecular, and serological detection of Trypanosoma cruzi I, II, and IV in blood of experimentally infected mice

APM Teston, AP de Abreu, AP Gruendling… - Experimental …, 2016 - Elsevier
Trypanosoma cruzi is the etiological agent of American trypanosomiasis (Chagas' disease),
which affects 6–7 million people worldwide, mainly in Latin America. It presents great …

Transferability of Trypanosoma cruzi from mixed human host infection to Triatoma infestans and from insects to axenic culture

S Ortiz, I Zulantay, W Apt, M Saavedra, A Solari - Parasitology international, 2015 - Elsevier
The etiologic agent of Chagas disease is Trypanosoma cruzi, a protozoan whose life cycle
involves obligatory passage through vertebrate and invertebrate hosts in a series of stages …

Trypanosoma cruzi: Multiplex PCR to detect and classify strains according to groups I and II

DB Liarte, SMF Murta, M Steindel… - Experimental parasitology, 2009 - Elsevier
A multiplex PCR was developed for simultaneous detection of Trypanosoma cruzi DNA and
classification of the parasite strain into groups I and II. As little as 10fg of T. cruzi DNA could …

Genotyping of Trypanosoma cruzi DTUs and Trypanosoma rangeli genetic groups in experimentally infected Rhodnius prolixus by PCR-RFLP

ARN Sá, GBM Dias, KY Kimoto, M Steindel, EC Grisard… - Acta tropica, 2016 - Elsevier
The specific detection and genetic typing of trypanosomes that infect humans, mammalian
reservoirs, and vectors is crucial for diagnosis and epidemiology. We utilized a PCR-RFLP …

Limit of detection of PCR/RFLP analysis of cytochrome oxidase II for the identification of genetic groups of Trypanosoma cruzi and Trypanosoma rangeli in biological …

ARN Sá, KY Kimoto, M Steindel, EC Grisard… - Parasitology …, 2018 - Springer
Mixed infections with Trypanosoma cruzi and Trypanosoma rangeli and their different
genetic groups occur frequently in vertebrate hosts and are difficult to detect by serology. In …