The causative agent of tuberculosis (TB), Mycobacterium tuberculosis and more recently
totally drug‐resistant strains of M. tuberculosis, display unique mechanisms to survive in the …

Free fatty acids and monoglycerides have long been known to possess broad-spectrum
antibacterial activity that is based on lytic behavior against bacterial cell membranes …

Summary The Core Elements of Outpatient Antibiotic Stewardship provides a framework for
antibiotic stewardship for outpatient clinicians and facilities that routinely provide antibiotic …

Importance The development of antibiotics is considered among the most important
advances of modern science. Antibiotics have saved millions of lives. However …

Background: Acute respiratory tract infection (ARTI) is the most common reason for antibiotic
prescription in adults. Antibiotics are often inappropriately prescribed for patients with ARTI …

Objectives To determine patterns of ambulatory antibiotic prescribing in US adults, including
the use of broad-spectrum versus narrow-spectrum agents, to provide a description of the …

Background. Appropriate antibiotic prescribing is an essential strategy to reduce the spread
of antibiotic resistance. US prescribing practices have not been thoroughly characterized …

Importance Nonguideline antibiotic prescribing for the treatment of pediatric infections is
common, but the consequences of inappropriate antibiotics are not well described. Objective …

Antibiotic overuse contributes to antibiotic resistance, which is a threat to public health.
Antibiotic stewardship is a practice dedicated to prescribing antibiotics only when necessary …

Mycobacterium tuberculosis (Mtb) infects one-third of the world's population and in 2013
accounted for 1.5 million deaths. Fluoroquinolone antibacterials, which target DNA gyrase …