Ubiquitylation is a major posttranslational modification that controls most complex aspects of
cell physiology. It is reversed through the action of a large family of deubiquitylating …

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Abstract Expression Atlas is EMBL-EBI's resource for gene and protein expression. It
sources and compiles data on the abundance and localisation of RNA and proteins in …

Biomedical research has been previously reported to primarily focus on a minority of all
known genes. Here, we demonstrate that these differences in attention can be explained, to …

Functional enrichment analysis or gene set enrichment analysis is a basic bioinformatics
method that evaluates the biological importance of a list of genes of interest. However, it may …

The FANTOM5 project investigates transcription initiation activities in more than 1,000
human and mouse primary cells, cell lines and tissues using CAGE. Based on manual …

Abstract Motivation: Transcription factor (TF) ChIP-seq datasets have particular
characteristics that provide unique challenges and opportunities for motif discovery. Most …

Abstract The RNA-Binding Protein DataBase (RBPDB) is a collection of experimental
observations of RNA-binding sites, both in vitro and in vivo, manually curated from primary …

The molecular basis for p53-mediated tumor suppression remains unclear. Here, to
elucidate mechanisms of p53 tumor suppression, we use knockin mice expressing an allelic …

Motivation: Describing biological sample variables with ontologies is complex due to the
cross-domain nature of experiments. Ontologies provide annotation solutions; however, for …