In the brain, astrocytes regulate shape and functions of the synaptic and vascular
compartments through a variety of released factors and membrane-bound proteins. An …

Ferroptosis is a newly discovered way of programmed cell death, mainly caused by the
accumulation of iron-dependent lipid peroxides in cells, which is morphologically …

Prolonged exposure to glucocorticoids, the main stress hormones, damages the brain and is
a risk factor for depression and Alzheimer's disease. Two major drivers of glucocorticoid …

Background Chronic stress and depression are potential risk factors for mild cognitive
impairment and dementia, including Alzheimer disease. The aim was to investigate whether …

Post-stroke depression (PSD) is a frequent and disabling complication of stroke that affects
up to one-third of stroke survivors. The pathophysiology of PSD involves multiple …

Objective This study aimed to evaluate the association between urinary heavy metal mixture
exposure and depression, and the modifying role of physical activity in the effects of heavy …

INTRODUCTION Depression is considered a prodromal state of Alzheimer's disease (AD),
yet the underlying mechanism (s) by which depression increases the risk of AD are not …

Depressive disorders are widely debilitating psychiatric disease. Despite the considerable
progress in the field of depression therapy, extensive research spanning many decades has …

Objectives: Repetitive transcranial magnetic stimulation (rTMS) has been considered as an
effective antidepressant treatment; however, the mechanism of its antidepressant effect is …

This review describes associations between dementia and loneliness on the
neurobiological and epidemiological levels according to the recent body of literature. The …