Long non-coding RNAs in lung cancer: Unraveling the molecular modulators of MAPK signaling

MS Hussain, O Afzal, G Gupta, ASA Altamimi… - … -Research and Practice, 2023 - Elsevier
Lung cancer (LC) continues to pose a significant global medical burden, necessitating a
comprehensive understanding of its molecular foundations to establish effective treatment …

Exploring the role of lncrna neat1 knockdown in regulating apoptosis across multiple cancer types: A review

MS Hussain, G Gupta, M Afzal, SM Alqahtani… - … -Research and Practice, 2023 - Elsevier
Long non-coding RNAs (lncRNAs) have emerged as pivotal regulators of gene expression,
contributing significantly to a diverse range of cellular processes, including apoptosis. One …

Long non-coding RNA NEAT1: a novel target for diagnosis and therapy in human tumors

P Dong, Y Xiong, J Yue, SJB Hanley… - Frontiers in …, 2018 - frontiersin.org
The nuclear paraspeckle assembly transcript 1 (NEAT1, a long non-coding RNA) is
frequently overexpressed in human tumors, and higher NEAT1 expression is correlated with …

NEAT 1: A novel cancer‐related long non‐coding RNA

X Yu, Z Li, H Zheng, MTV Chan, WKK Wu - Cell proliferation, 2017 - Wiley Online Library
Aberrant overexpression of the long non‐coding RNA NEAT 1 (nuclear paraspeckle
assembly transcript 1) has been documented in different types of solid tumours, such as lung …

Matrix factorization-based data fusion for the prediction of lncRNA–disease associations

G Fu, J Wang, C Domeniconi, G Yu - Bioinformatics, 2018 - academic.oup.com
Abstract Motivation Long non-coding RNAs (lncRNAs) play crucial roles in complex disease
diagnosis, prognosis, prevention and treatment, but only a small portion of lncRNA–disease …

Neat1 is a p53-inducible lincRNA essential for transformation suppression

SS Mello, C Sinow, N Raj, PK Mazur… - Genes & …, 2017 - genesdev.cshlp.org
The p53 gene is mutated in over half of all cancers, reflecting its critical role as a tumor
suppressor. Although p53 is a transcriptional activator that induces myriad target genes …

LncRNAs with miRNAs in regulation of gastric, liver, and colorectal cancers: updates in recent years

C Tam, JH Wong, SKW Tsui, T Zuo, TF Chan… - Applied microbiology and …, 2019 - Springer
Long noncoding RNA (lncRNA) is a kind of RNAi molecule composed of hundreds to
thousands of nucleotides. There are several major types of functional lncRNAs which …

Long noncoding RNA-enriched vesicles secreted by hypoxic cardiomyocytes drive cardiac fibrosis

F Kenneweg, C Bang, K Xiao, CM Boulanger… - … Therapy-Nucleic Acids, 2019 - cell.com
Long non-coding RNAs (lncRNAs) have potential as novel therapeutic targets in
cardiovascular diseases, but detailed information about the intercellular lncRNA shuttling …

Role of noncoding RNA in drug resistance of prostate cancer

L Ding, R Wang, D Shen, S Cheng, H Wang, Z Lu… - Cell death & …, 2021 - nature.com
Prostate cancer is one of the most prevalent forms of cancer around the world. Androgen-
deprivation treatment and chemotherapy are the curative approaches used to suppress …

SDLDA: lncRNA-disease association prediction based on singular value decomposition and deep learning

M Zeng, C Lu, F Zhang, Y Li, FX Wu, Y Li, M Li - Methods, 2020 - Elsevier
In recent years, accumulating studies have shown that long non-coding RNAs (lncRNAs) not
only play an important role in the regulation of various biological processes but also are the …