Colchicine ameliorates 5‐Fluorouracil‐Induced cardiotoxicity in rats

S Safarpour, S Safarpour, M Pirzadeh… - Oxidative Medicine …, 2022 - Wiley Online Library
Background and Objective. 5‐Fluorouracil is one of the most common chemotherapeutic
agents used in the treatment of solid tumors. 5‐Fluorouracil‐associated cardiotoxicity is the …

Maintenance capecitabine and bevacizumab versus bevacizumab alone after initial first-line bevacizumab and docetaxel for patients with HER2-negative metastatic …

J Gligorov, D Doval, J Bines, E Alba, P Cortes… - The Lancet …, 2014 - thelancet.com
Background Longer duration of first-line chemotherapy for patients with metastatic breast
cancer is associated with prolonged overall survival and improved progression-free survival …

Protective effect of kaempferol and its nanoparticles on 5‐fluorouracil‐induced cardiotoxicity in rats

S Safarpour, M Pirzadeh, A Ebrahimpour… - BioMed Research …, 2022 - Wiley Online Library
Background. Fluorouracil (5‐FU) is the third most common chemotherapeutic agent used in
the treatment of solid tumors. 5‐FU‐associated cardiotoxicity ranks the second causes of …

Paris saponin I induces apoptosis via increasing the Bax/Bcl‑2 ratio and caspase‑3 expression in gefitinib‑resistant non‑small cell lung cancer in vitro and in vivo

H Jiang, PJ Zhao, D Su, J Feng… - Molecular Medicine …, 2014 - spandidos-publications.com
Polyphyllins, a major component of Rhizoma paridis, have been extensively used in non‑
small cell lung cancer (NSCLC). The aim of the present study was to evaluate the effects of …

Exopolysaccharide from Cryptococcus heimaeyensis S20 induces autophagic cell death in non‐small cell lung cancer cells via ROS/p38 and ROS/ERK signalling

Y Hao, Y Huang, J Chen, J Li, Y Yuan, M Wang… - Cell …, 2020 - Wiley Online Library
Objectives Cryptococcus heimaeyensis S20 is found in Antarctica and can produce
exopolysaccharides (CHEPS). Here, we explore the anti‐tumour effects of CHEPS on non …

Immune checkpoint inhibitors as switch or continuation maintenance therapy in solid tumors: rationale and current state

P Grivas, BJ Monk, D Petrylak, M Reck, G Foley… - Targeted …, 2019 - Springer
First-line chemotherapy for many solid tumors is limited by toxicity. There is a growing
interest in maintenance therapy as a strategy for prolonging the benefits of first-line therapy …

[HTML][HTML] Mechanism and potential predictive biomarkers of immune checkpoint inhibitors in NSCLC

J Qu, M Jiang, L Wang, D Zhao, K Qin, Y Wang… - Biomedicine & …, 2020 - Elsevier
Lung cancer is currently the highest morbidity and mortality malignancy all over the world. In
the past, the treatment options available for patients with lung cancer were mainly …

Traditional Chinese Medicine treatment as maintenance therapy in advanced non-small-cell lung cancer: a randomized controlled trial

Y Jiang, LS Liu, LP Shen, ZF Han, H Jian, JX Liu… - … Therapies in Medicine, 2016 - Elsevier
Objectives Maintenance therapy for patients with advanced non-small-cell lung cancer
(NSCLC) is an increasingly hot topic in the field of clinical NSCLC research. This study …

Long-Lasting Therapeutic Response following Treatment with Pembrolizumab in Patients with Non-Small Cell Lung Cancer: A Real-World Experience

W Shalata, J Zolnoorian, G Migliozzi, AA Jama… - International Journal of …, 2023 - mdpi.com
Immune checkpoint inhibitors (ICIs), pembrolizumab in particular, have been shown to be
vastly more efficacious than traditional cytotoxic or platinum-based chemotherapies in the …

Canine indolent and aggressive lymphoma: clinical spectrum with histologic correlation

L Aresu, V Martini, F Rossi, M Vignoli… - Veterinary and …, 2015 - Wiley Online Library
Sixty‐three dogs with newly diagnosed lymphoma underwent complete staging and
received the same chemotherapy. Diffuse large B‐cell lymphoma was the leading histotype …