A review about pembrolizumab in first-line treatment of advanced NSCLC: focus on KEYNOTE studies

J Qu, L Wang, M Jiang, D Zhao, Y Wang… - Cancer Management …, 2020 - Taylor & Francis
Lung cancer is currently the malignant tumor with the highest incidence and mortality in the
world, while non-small cell lung cancer (NSCLC) is the most common pathological type of …

[HTML][HTML] Multi-center real-world outcomes of nivolumab plus ipilimumab and chemotherapy in patients with metastatic non-small-cell lung cancer

W Shalata, A Yakobson, Y Dudnik, F Swaid, MS Ahmad… - Biomedicines, 2023 - mdpi.com
Immune checkpoint inhibitors have become the standard of care in the treatment of
metastatic non-small-cell lung cancer (NSCLC). The combination of nivolumab plus …

[HTML][HTML] Metastatic pancreatic cancer: Is there a light at the end of the tunnel?

V Vaccaro, I Sperduti, S Vari, E Bria… - World journal of …, 2015 - ncbi.nlm.nih.gov
Due to extremely poor prognosis, pancreatic cancer (PDAC) represents the fourth leading
cause of cancer-related death in Western countries. For more than a decade, gemcitabine …

[HTML][HTML] Modern therapies of nonsmall cell lung cancer

A Jachowski, M Marcinkowski, J Szydłowski… - Journal of Applied …, 2023 - Springer
Lung cancer (LC), particularly nonsmall cell lung cancer (NSCLC), is one of the most
prevalent types of neoplasia worldwide, regardless of gender, with the highest mortality …

Estimation of tumour regression and growth rates during treatment in patients with advanced prostate cancer: a retrospective analysis

J Wilkerson, K Abdallah, C Hugh-Jones, G Curt… - The Lancet …, 2017 - thelancet.com
Background We applied mathematical models to clinical trial data available at Project Data
Sphere LLC (Cary, NC, USA), a non-profit universal access data-sharing warehouse. Our …

[HTML][HTML] Genomic alteration during metastasis of lung adenocarcinoma

Q Tan, J Cui, J Huang, Z Ding, H Lin, X Niu… - Cellular Physiology and …, 2016 - karger.com
Background/Aims: Recurrent gene mutation has been identified by the analysis of exonic
DNA from lung adenocarcinoma, but its progression has not been extensively profiled. The …

[HTML][HTML] Advances in the lung cancer immunotherapy approaches

H Padinharayil, RR Alappat, LM Joy, KV Anilkumar… - Vaccines, 2022 - mdpi.com
Despite the progress in the comprehension of LC progression, risk, immunologic control,
and treatment choices, it is still the primary cause of cancer-related death. LC cells possess …

Inhibition of microRNA-196a might reverse cisplatin resistance of A549/DDP non-small-cell lung cancer cell line

JH Li, N Luo, MZ Zhong, ZQ Xiao, JX Wang, XY Yao… - Tumor Biology, 2016 - Springer
We aimed to explore the possible mechanism of microRNA-196a (miR-196a) inhibition and
reversion of drug resistance to cisplatin (DDP) of the A549/DDP non-small-cell lung cancer …

[HTML][HTML] Landscape of circular RNAs in different types of lung cancer and an emerging role in therapeutic resistance

F Wang, C Yu, L Chen, S Xu - … journal of oncology, 2023 - spandidos-publications.com
Lung cancer is one of the most common malignant tumor types and the leading cause of
cancer-associated death worldwide. Different types of lung cancer exhibit differences in …

[HTML][HTML] Maintenance chemotherapy using S-1 following definitive chemoradiotherapy in patients with N3 nasopharyngeal carcinoma

J Zong, H Xu, B Chen, Q Guo, Y Xu, C Chen, Y Weng… - Radiation …, 2019 - Springer
Background Patients with N3 stage nasopharyngeal carcinoma (NPC) are at high risk for
treatment failure. This study aims to assess the efficacy of maintenance chemotherapy (MC) …