International consensus statement on allergy and rhinology: Allergic rhinitis–2023

SK Wise, C Damask, LT Roland, C Ebert… - International forum of …, 2023 - Wiley Online Library
Background In the 5 years that have passed since the publication of the 2018 International
Consensus Statement on Allergy and Rhinology: Allergic Rhinitis (ICAR‐Allergic Rhinitis …

Endotypes of chronic rhinosinusitis: relationships to disease phenotypes, pathogenesis, clinical findings, and treatment approaches

A Kato, AT Peters, WW Stevens, RP Schleimer… - Allergy, 2022 - Wiley Online Library
Chronic rhinosinusitis (CRS) is a common clinical syndrome that produces significant
morbidity and costs to our health system. The study of CRS has progressed from an era …

Efficacy and safety of benralizumab in chronic rhinosinusitis with nasal polyps: a randomized, placebo-controlled trial

C Bachert, JK Han, MY Desrosiers, P Gevaert… - Journal of Allergy and …, 2022 - Elsevier
Background Eosinophilic inflammation has been implicated in the pathogenesis, severity,
and treatment responsiveness of chronic rhinosinusitis with nasal polyps (CRSwNP) …

Epidemiology of chronic rhinosinusitis: prevalence and risk factors

AR Sedaghat, EC Kuan, GK Scadding - The Journal of Allergy and Clinical …, 2022 - Elsevier
Knowledge of chronic rhinosinusitis (CRS) epidemiology may directly impact patient care:
aiding patient identification and establishing accurate diagnosis as well as informing …

International consensus statement on allergy and rhinology: olfaction

ZM Patel, EH Holbrook, JH Turner… - International forum of …, 2022 - Wiley Online Library
Background The literature regarding clinical olfaction, olfactory loss, and olfactory
dysfunction has expanded rapidly over the past two decades, with an exponential rise in the …

Endoscopic sinus surgery with medical therapy versus medical therapy for chronic rhinosinusitis with nasal polyps: a multicentre, randomised, controlled trial

ES Lourijsen, S Reitsma, M Vleming… - The Lancet …, 2022 - thelancet.com
Background Endoscopic sinus surgery (ESS) is a common operation for patients with
chronic rhinosinusitis with nasal polyps (CRSwNP) when medical therapy alone is …

Prognostic factors for polyp recurrence in chronic rhinosinusitis with nasal polyps

J Bai, JH Huang, CPE Price, JM Schauer… - Journal of Allergy and …, 2022 - Elsevier
Background Chronic rhinosinusitis with nasal polyps is frequently managed with endoscopic
sinus surgery (ESS). Prior studies describe individual clinical variables and eosinophil …

Type 2 chronic inflammatory diseases: targets, therapies and unmet needs

P Kolkhir, CA Akdis, M Akdis, C Bachert… - Nature Reviews Drug …, 2023 - nature.com
Over the past two decades, significant progress in understanding of the pathogenesis of type
2 chronic inflammatory diseases has enabled the identification of compounds for more than …

[HTML][HTML] Chronic rhinosinusitis with nasal polyps: quality of life in the biologics era

J Mullol, A Azar, KM Buchheit, C Hopkins… - The Journal of Allergy …, 2022 - Elsevier
Chronic rhinosinusitis (CRS) affects up to 12% of the general population and is traditionally
divided into two main phenotypic subsets, based on the presence of nasal polyps …

Inflammatory molecular endotypes of nasal polyps derived from White and Japanese populations

T Nakayama, IT Lee, W Le, Y Tsunemi… - Journal of Allergy and …, 2022 - Elsevier
Background Emerging evidence suggests that chronic rhinosinusitis with nasal polyps
(CRSwNP) is a highly heterogeneous disease with disparate inflammatory characteristics …