Evolution and diversity of assembly-line polyketide synthases: Focus review
Assembly-line polyketide synthases (PKSs) are among the most complex protein
machineries known in nature, responsible for the biosynthesis of numerous compounds …
machineries known in nature, responsible for the biosynthesis of numerous compounds …
Molecular diversity sculpted by fungal PKS–NRPS hybrids
D Boettger, C Hertweck - ChemBioChem, 2013 - Wiley Online Library
Fungal polyketide synthase–nonribosomal peptide synthetase (PKS–NRPS) hybrids
manufacture a wide range of structurally diverse secondary metabolites that play an eminent …
manufacture a wide range of structurally diverse secondary metabolites that play an eminent …
Atlas of nonribosomal peptide and polyketide biosynthetic pathways reveals common occurrence of nonmodular enzymes
Nonribosomal peptides and polyketides are a diverse group of natural products with
complex chemical structures and enormous pharmaceutical potential. They are synthesized …
complex chemical structures and enormous pharmaceutical potential. They are synthesized …
Navigating the fungal polyketide chemical space: from genes to molecules
The iterative type I polyketide synthases (IPKSs) are central to the biosynthesis of an
enormously diverse array of natural products in fungi. These natural products, known as …
enormously diverse array of natural products in fungi. These natural products, known as …
Discovering the secondary metabolite potential encoded within entomopathogenic fungi
DM Gibson, BGG Donzelli, SB Krasnoff… - Natural Product …, 2014 - pubs.rsc.org
Discovering the secondary metabolite potential encoded within entomopathogenic fungi -
Natural Product Reports (RSC Publishing) DOI:10.1039/C4NP00054D Royal Society of …
Natural Product Reports (RSC Publishing) DOI:10.1039/C4NP00054D Royal Society of …
At the nexus of three kingdoms: the genome of the mycorrhizal fungus Gigaspora margarita provides insights into plant, endobacterial and fungal interactions
F Venice, S Ghignone… - Environmental …, 2020 - Wiley Online Library
As members of the plant microbiota, arbuscular mycorrhizal fungi (AMF, Glomeromycotina)
symbiotically colonize plant roots. AMF also possess their own microbiota, hosting some …
symbiotically colonize plant roots. AMF also possess their own microbiota, hosting some …
Bioprospecting Trichoderma: A Systematic Roadmap to Screen Genomes and Natural Products for Biocontrol Applications
TA Rush, HK Shrestha… - Frontiers in Fungal …, 2021 - frontiersin.org
Natural products derived from microbes are crucial innovations that would help in reaching
sustainability development goals worldwide while achieving bioeconomic growth …
sustainability development goals worldwide while achieving bioeconomic growth …
Fungal metabolic gene clusters—caravans traveling across genomes and environments
JH Wisecaver, A Rokas - Frontiers in microbiology, 2015 - frontiersin.org
Metabolic gene clusters (MGCs), physically co-localized genes participating in the same
metabolic pathway, are signature features of fungal genomes. MGCs are most often …
metabolic pathway, are signature features of fungal genomes. MGCs are most often …
An update to polyketide synthase and non-ribosomal synthetase genes and nomenclature in Fusarium
Members of the genus Fusarium produce a plethora of bioactive secondary metabolites,
which can be harmful to humans and animals or have potential in drug development. In this …
which can be harmful to humans and animals or have potential in drug development. In this …
Genomic and transcriptomic analysis of the endophytic fungus Pestalotiopsis fici reveals its lifestyle and high potential for synthesis of natural products
X Wang, X Zhang, L Liu, M Xiang, W Wang, X Sun… - BMC genomics, 2015 - Springer
Background In recent years, the genus Pestalotiopsis is receiving increasing attention, not
only because of its economic impact as a plant pathogen but also as a commonly isolated …
only because of its economic impact as a plant pathogen but also as a commonly isolated …