Of the currently known 140 species in the family Reduviidae, subfamily Triatominae, those
which are most important as vectors of the aetiologic agent of Chagas disease …

Bats (order Chiroptera) have been increasingly recognised as important reservoir hosts for
human and animal pathogens worldwide. In this context, molecular and microscopy-based …

The intergenic region of spliced-leader (SL-IR) genes from 105 Trypanosoma cruzi I (Tc I)
infected biological samples, culture isolates and stocks from 11 endemic countries, from …

The genetic palette from which the spectrum of variability in Trypanosoma cruzi has been
drawn is astonishingly limited. In this review we address the roots of this unusual pedigree …

Background The evolutionary history and ecological associations of Trypanosoma cruzi, the
need to identify genetic markers that can distinguish parasite subpopulations, and …

Introduction. The current chemotherapy for Chagas disease is unsatisfactory with only two
drugs available for treatment. Research to discover new drugs for Chagas disease is urgent …

Background Trypanosoma cruzi, the hemoparasite that causes Chagas disease, is divided
into six Discrete Typing Units or DTUs: TcI-TcVI plus Tcbat. This genetic diversity is based on …

The genotypic structure of parasite populations is an important determinant of ecological
and evolutionary dynamics of host-parasite interactions with consequences for pest …

Trypanosoma cruzi is genetically classified into at least two major lineages named T. cruzi I
(also named Tc I) and T. cruzi II (also named Tc IIb). T. cruzi II is associated with Chagas' …

Genotyping studies show a polarized geographic distribution of Trypanosoma cruzi lineages
in humans. Here, we assessed their distribution along Latin America through an …