[HTML][HTML] Update on the applications and limitations of alpha-fetoprotein for hepatocellular carcinoma

H Hanif, MJ Ali, AT Susheela, IW Khan… - World Journal of …, 2022 - ncbi.nlm.nih.gov
Alpha-fetoprotein (AFP) is an oncofetal glycoprotein that has been used as a tumor marker
for hepatocellular carcinoma (HCC) in combination with ultrasound and other imaging …

New blood biomarkers for the diagnosis of AFP-negative hepatocellular carcinoma

T Wang, KH Zhang - Frontiers in Oncology, 2020 - frontiersin.org
An early diagnosis of hepatocellular carcinoma (HCC) followed by effective treatment is
currently critical for improving the prognosis and reducing the associated economic burden …

[PDF][PDF] Progress and challenges of predictive biomarkers for immune checkpoint blockade

Y Lei, X Li, Q Huang, X Zheng, M Liu - Frontiers in Oncology, 2021 - frontiersin.org
Over the past decade, immune checkpoint blockade (ICB) therapy has revolutionized the
outlook for oncology with significant and sustained improvement in the overall patient …

Evaluation of lactate dehydrogenase and alkaline phosphatase as predictive biomarkers in the prognosis of hepatocellular carcinoma and development of a new …

K Su, W Huang, X Li, K Xu, T Gu, Y Liu… - Journal of …, 2023 - Taylor & Francis
Background Tumor proliferation is frequently accompanied by aberrant enzyme production.
We aim to investigate the potential predictive value of both plasma alkaline phosphatase …

Cell-free DNA methylation markers for differential diagnosis of hepatocellular carcinoma

B Luo, F Ma, H Liu, J Hu, L Rao, C Liu, Y Jiang… - BMC medicine, 2022 - Springer
Background Aberrant DNA methylation may offer opportunities in revolutionizing cancer
screening and diagnosis. We sought to identify a non-invasive DNA methylation-based …

Plant‐derived lectins as potential cancer therapeutics and diagnostic tools

M Mazalovska, JC Kouokam - BioMed Research International, 2020 - Wiley Online Library
Cancer remains a global health challenge, with high morbidity and mortality, despite the
recent advances in diagnosis and treatment. Multiple compounds assessed as novel …

Risk factors and prevention of viral hepatitis-related hepatocellular carcinoma

X Zhang, L Guan, H Tian, Z Zeng, J Chen… - Frontiers in …, 2021 - frontiersin.org
Hepatocellular carcinoma (HCC) is a common cancer in the world, and its incidence is
increasing yearly. Hepatitis B virus (HBV) infection and hepatitis C virus (HCV) infection are …

hsa_circ_0003410 promotes hepatocellular carcinoma progression by increasing the ratio of M2/M1 macrophages through the miR‐139‐3p/CCL5 axis

P Cao, B Ma, D Sun, W Zhang, J Qiu, L Qin… - Cancer …, 2022 - Wiley Online Library
Noncoding RNAs have been verified to regulate the infiltration of macrophages to accelerate
tumor biological progression, however the regulation of macrophages by circular RNAs in …

Diagnostic significance of hsa-miR-21-5p, hsa-miR-192-5p, hsa-miR-155-5p, hsa-miR-199a-5p panel and ratios in hepatocellular carcinoma on top of liver cirrhosis in …

MA Eldosoky, R Hammad, AA Elmadbouly… - International journal of …, 2023 - mdpi.com
Early hepatocellular carcinoma (HCC) diagnosis is challenging. Moreover, for patients with
alpha-fetoprotein (AFP)-negative HCC, this challenge is augmented. MicroRNAs (miRs) …

The use of minimally invasive biomarkers for the diagnosis and prognosis of hepatocellular carcinoma

LTF de Lima, D Broszczak, X Zhang, K Bridle… - … et Biophysica Acta (BBA …, 2020 - Elsevier
Hepatocellular carcinoma (HCC) is a common cause of cancer-related deaths worldwide.
Despite advances in systemic therapies, patient survival remains low due to late diagnosis …