Small molecule metabolites: discovery of biomarkers and therapeutic targets
S Qiu, Y Cai, H Yao, C Lin, Y Xie, S Tang… - Signal Transduction and …, 2023 - nature.com
Metabolic abnormalities lead to the dysfunction of metabolic pathways and metabolite
accumulation or deficiency which is well-recognized hallmarks of diseases. Metabolite …
accumulation or deficiency which is well-recognized hallmarks of diseases. Metabolite …
Osteoporosis pathogenesis and treatment: existing and emerging avenues
B Liang, G Burley, S Lin, YC Shi - Cellular & Molecular Biology Letters, 2022 - Springer
Osteoporotic fractures lead to increased disability and mortality in the elderly population.
With the rapid increase in the aging population around the globe, more effective treatments …
With the rapid increase in the aging population around the globe, more effective treatments …
Biomaterials and nanomedicine for bone regeneration: Progress and future prospects
Bone defects pose a heavy burden on patients, orthopedic surgeons, and public health
resources. Various pathological conditions cause bone defects including trauma, tumors …
resources. Various pathological conditions cause bone defects including trauma, tumors …
FunRich enables enrichment analysis of OMICs datasets
High‐throughput methods to profile the genome, transcriptome, proteome and metabolome
of various systems has become a routine in multiple research laboratories around the world …
of various systems has become a routine in multiple research laboratories around the world …
Molecular mechanisms and emerging therapeutics for osteoporosis
JY Noh, Y Yang, H Jung - International journal of molecular sciences, 2020 - mdpi.com
Osteoporosis is the most common chronic metabolic bone disease. It has been estimated
that more than 10 million people in the United States and 200 million men and women …
that more than 10 million people in the United States and 200 million men and women …
Advances in materials-based therapeutic strategies against osteoporosis
C Lei, J Song, S Li, Y Zhu, M Liu, M Wan, Z Mu, FR Tay… - Biomaterials, 2023 - Elsevier
Osteoporosis is caused by the disruption in homeostasis between bone formation and bone
resorption. Conventional management of osteoporosis involves systematic drug …
resorption. Conventional management of osteoporosis involves systematic drug …
The development of molecular biology of osteoporosis
Y Gao, S Patil, J Jia - International journal of molecular sciences, 2021 - mdpi.com
Osteoporosis is one of the major bone disorders that affects both women and men, and
causes bone deterioration and bone strength. Bone remodeling maintains bone mass and …
causes bone deterioration and bone strength. Bone remodeling maintains bone mass and …
[HTML][HTML] High proportion strontium-doped micro-arc oxidation coatings enhance early osseointegration of titanium in osteoporosis by anti-oxidative stress pathway
X Shen, K Fang, KHR Yie, Z Zhou, Y Shen, S Wu… - Bioactive Materials, 2022 - Elsevier
The excessive accumulation of reactive oxygen species (ROS) under osteoporosis
precipitates a microenvironment with high levels of oxidative stress (OS). This could …
precipitates a microenvironment with high levels of oxidative stress (OS). This could …
A review of integrative imputation for multi-omics datasets
Multi-omics studies, which explore the interactions between multiple types of biological
factors, have significant advantages over single-omics analysis for their ability to provide a …
factors, have significant advantages over single-omics analysis for their ability to provide a …
Insights and implications of sexual dimorphism in osteoporosis
Osteoporosis, a metabolic bone disease characterized by low bone mineral density and
deterioration of bone microarchitecture, has led to a high risk of fatal osteoporotic fractures …
deterioration of bone microarchitecture, has led to a high risk of fatal osteoporotic fractures …