Origins of modern human ancestry

A Bergström, C Stringer, M Hajdinjak, EML Scerri… - Nature, 2021 - nature.com
New finds in the palaeoanthropological and genomic records have changed our view of the
origins of modern human ancestry. Here we review our current understanding of how the …

Ancient DNA analysis

L Orlando, R Allaby, P Skoglund… - Nature reviews …, 2021 - nature.com
Although the first ancient DNA molecules were extracted more than three decades ago, the
first ancient nuclear genomes could only be characterized after high-throughput sequencing …

[HTML][HTML] The Allen Ancient DNA Resource (AADR) a curated compendium of ancient human genomes

S Mallick, A Micco, M Mah, H Ringbauer, I Lazaridis… - Scientific Data, 2024 - nature.com
More than two hundred papers have reported genome-wide data from ancient humans.
While the raw data for the vast majority are fully publicly available testifying to the …

[HTML][HTML] The major genetic risk factor for severe COVID-19 is inherited from Neanderthals

H Zeberg, S Pääbo - Nature, 2020 - nature.com
A recent genetic association study identified a gene cluster on chromosome 3 as a risk locus
for respiratory failure after infection with severe acute respiratory syndrome coronavirus 2 …

A global catalog of whole-genome diversity from 233 primate species

LFK Kuderna, H Gao, MC Janiak, M Kuhlwilm, JD Orkin… - Science, 2023 - science.org
The rich diversity of morphology and behavior displayed across primate species provides an
informative context in which to study the impact of genomic diversity on fundamental …

[HTML][HTML] The structure, function and evolution of a complete human chromosome 8

GA Logsdon, MR Vollger, PH Hsieh, Y Mao… - Nature, 2021 - nature.com
The complete assembly of each human chromosome is essential for understanding human
biology and evolution,. Here we use complementary long-read sequencing technologies to …

A genomic region associated with protection against severe COVID-19 is inherited from Neandertals

H Zeberg, S Pääbo - … of the National Academy of Sciences, 2021 - National Acad Sciences
It was recently shown that the major genetic risk factor associated with becoming severely ill
with COVID-19 when infected by severe acute respiratory syndrome coronavirus 2 (SARS …

[HTML][HTML] Initial Upper Palaeolithic humans in Europe had recent Neanderthal ancestry

M Hajdinjak, F Mafessoni, L Skov, B Vernot, A Hübner… - Nature, 2021 - nature.com
Modern humans appeared in Europe by at least 45,000 years ago 1, 2, 3, 4, 5, but the extent
of their interactions with Neanderthals, who disappeared by about 40,000 years ago 6, and …

[HTML][HTML] Genetic insights into the social organization of Neanderthals

L Skov, S Peyrégne, D Popli, LNM Iasi, T Devièse… - Nature, 2022 - nature.com
Genomic analyses of Neanderthals have previously provided insights into their population
history and relationship to modern humans 1, 2, 3, 4, 5, 6, 7, 8, but the social organization of …

Unearthing Neanderthal population history using nuclear and mitochondrial DNA from cave sediments

B Vernot, EI Zavala, A Gómez-Olivencia, Z Jacobs… - Science, 2021 - science.org
INTRODUCTION The study of hominin history has progressed through both archaeological
and genetic insights. Although DNA sequencing from hominin skeletal remains allows the …