Non-coding RNAs (ncRNAs) and multidrug resistance in glioblastoma: Therapeutic challenges and opportunities
GM Subaiea, RU Syed, S Afsar, TMS Alhaidan… - … -Research and Practice, 2023 - Elsevier
Non-coding RNAs (ncRNAs) have been recognized as pivotal regulators of transcriptional
and post-transcriptional gene modulation, exerting a profound influence on a diverse array …
and post-transcriptional gene modulation, exerting a profound influence on a diverse array …
[HTML][HTML] HB5 aptamer-tagged graphene oxide for co-delivery of doxorubicin and silibinin, and highly effective combination therapy in breast cancer
M Shahidi, BF Haghiralsadat, O Abazari… - Cancer …, 2023 - Springer
Using a chemotherapeutic agent, such as doxorubicin (DOX), with a natural agent, such as
silibinin (Sili), is highly valuable to minimize systemic toxicity. However, Sili and DOX face …
silibinin (Sili), is highly valuable to minimize systemic toxicity. However, Sili and DOX face …
Survival outcomes and efficacy of platinum in early breast cancer patients with germline BRCA1 or BRCA2 mutation: a multicenter retrospective cohort study
X Chen, X Qian, M Xiao, P Zhang - Breast Cancer: Targets and …, 2023 - Taylor & Francis
Purpose The study aimed to compare the survival outcomes and efficacy of platinum in early
breast cancer patients with BRCA1 and BRCA2 mutations. Methods Patients diagnosed with …
breast cancer patients with BRCA1 and BRCA2 mutations. Methods Patients diagnosed with …
[HTML][HTML] Impact of nanocarrier aggregation on EPR-mediated tumor targeting
SP Surya Teja, N Damodharan… - … in Bioengineering and …, 2023 - frontiersin.org
The aim of this study was to investigate the influence of excipients on retaining the particle
size of methotrexate (MTX) loaded chitosan nanocarriers (CsNP) during lyophilization …
size of methotrexate (MTX) loaded chitosan nanocarriers (CsNP) during lyophilization …
Exploring ncRNAs in epilepsy: From oxidative stress regulation to therapy
Epilepsy is a prevalent neurological illness which is linked with high worldwide burdens.
Oxidative stress (OS) is recognized to be among the contributors that trigger the …
Oxidative stress (OS) is recognized to be among the contributors that trigger the …
[HTML][HTML] Relationship between long non-coding RNAs and Hippo signaling pathway in gastrointestinal cancers; molecular mechanisms and clinical significance
Long non-coding RNAs (lncRNAs) play a significant biological role in the regulation of
various cellular processes such as cell proliferation, differentiation, apoptosis and migration …
various cellular processes such as cell proliferation, differentiation, apoptosis and migration …
Exploring Ubiquitin-Specific Proteases as Therapeutic Targets in Glioblastoma
Glioblastoma (GB) remains a formidable challenge and requires new treatment strategies.
The vital part of the ubiquitin-proteasome system (UPS) in cellular regulation has positioned …
The vital part of the ubiquitin-proteasome system (UPS) in cellular regulation has positioned …
[HTML][HTML] Ferroptosis and circular RNAs: new horizons in cancer therapy
Cancer poses intricate challenges to treatment due to its complexity and diversity.
Ferroptosis and circular RNAs (circRNAs) are emerging as innovative therapeutic avenues …
Ferroptosis and circular RNAs (circRNAs) are emerging as innovative therapeutic avenues …
[HTML][HTML] A clinical prognostic model of oxidative stress-related genes linked to tumor immune cell infiltration and the prognosis of ovarian cancer patients
L Li, W Zhang, Y Sun, W Zhang, M Lu, J Wang, Y Jin… - Heliyon, 2024 - cell.com
Background According to statistics, ovarian cancer (OV) is the most prevalent type of
gynecologic malignancy and has the highest mortality rate of all gynecologic tumors …
gynecologic malignancy and has the highest mortality rate of all gynecologic tumors …
[HTML][HTML] Biological Activity of Oleanolic Acid Derivatives HIMOXOL and Br-HIMOLID in Breast Cancer Cells Is Mediated by ER and EGFR
N Lisiak, P Dzikowska, U Wisniewska… - International Journal of …, 2023 - mdpi.com
Breast cancer is one of the most frequently observed malignancies worldwide and
represents a heterogeneous group of cancers. For this reason, it is crucial to properly …
represents a heterogeneous group of cancers. For this reason, it is crucial to properly …