Simple Summary Patients with gliomas experience worsened quality of life due to epileptic
attacks. Over 80% of patients are susceptible to seizures, significantly hindering their …

Tumor suppressor p53 can transcriptionally activate downstream genes in response to
stress, and then regulate the cell cycle, DNA repair, metabolism, angiogenesis, apoptosis …

Abstract Salvigenin is a Trimethoxylated Flavone enriched in Scutellariae Barbatae Herba
and Scutellariae Radix and is demonstrated to have anti-tumor properties in colon cancer …

Glioblastoma (GBM), one of the most aggressive forms of brain cancer, has limited treatment
options. Recent years have witnessed the remarkable success of checkpoint inhibitor …

The global challenge posed by cancer, marked by rising incidence and mortality rates,
underscores the urgency for innovative therapeutic approaches. The PI3K/Akt signaling …

In addition to environmental conditions, lifestyle factors, and chemical exposure, aberrant
gene expression and mutations involve in the beginning and development of urological …

Background Glioblastoma multiforme (GBM) is a devastating disease that lacks effective
drugs for targeted therapy. Previously, we found that the third-generation epidermal growth …

Glioblastoma (GBM) is a representative malignant brain tumor characterized by a dismal
prognosis, with survival rates of less than 2 years and high recurrence rates. Despite …

Introduction Gliomas represent the most prevalent and aggressive tumors within the central
nervous system. Despite the current standard treatments, the median survival time for …

Solute carrier (SLC), a diverse family of membrane proteins, are instrumental in
orchestrating the intake and efflux of nutrients including amino acids, vitamins, ions …