Selenium chemistry for spatio-selective peptide and protein functionalization

Z Zhao, S Laps, JS Gichtin, N Metanis - Nature Reviews Chemistry, 2024 - nature.com
The ability to construct a peptide or protein in a spatio-specific manner is of great interest for
therapeutic and biochemical research. However, the various functional groups present in …

External stimulation-controlled dynamic DNA devices for biosensing and biomedical applications

W Xu, F Hu, J Li, J Shang, X Liu, Y Zeng, Q Wu… - Science China …, 2023 - Springer
DNA devices that can recognize molecular inputs and transform them into functional outputs
in an autonomous manner have been actively pursued as versatile toolkits for controlled …

A pH‐Cascaded DNA Hydrogel Mediated by Reconfigurable A‐motif Duplex, i‐Motif Quadruplex, and T· A‐T Triplex Structures

Y Hu, Y Ke, I Willner - Advanced Functional Materials, 2023 - Wiley Online Library
Governed by pH‐configurable A‐motif, i‐motif and T· A‐T triplex configurations, a cascaded
DNA hydrogel subjecting to diverse pH values is presented. Under highly acidic conditions …

Transient Dynamic Operation of G-Quadruplex-Gated Glucose Oxidase-Loaded ZIF-90 Metal–Organic Framework Nanoparticle Bioreactors

Y Qin, Y Ouyang, J Wang, X Chen, YS Sohn… - Nano Letters, 2023 - ACS Publications
Glucose oxidase-loaded ZIF-90 metal–organic framework nanoparticles conjugated to
hemin-G-quadruplexes act as functional bioreactor hybrids operating transient dissipative …

Programming the Assembly of Oligo-Adenine with Coralyne into a pH-Responsive DNA Hydrogel

SR Lee, CYJ Ong, JY Wong, Y Ke… - … Applied Materials & …, 2024 - ACS Publications
External stimuli-responsive DNA hydrogels present interesting platforms for drug loading
and triggered release. Typically, drug molecules are encapsulated within three …

Light-controlled growth of DNA organelles in synthetic cells

S Agarwal, M Dizani, D Osmanovic… - Interface …, 2023 - royalsocietypublishing.org
Living cells regulate many of their vital functions through dynamic, membraneless
compartments that phase separate (condense) in response to different types of stimuli. In …

Leveraging Aptamer-Based DNA Nanotechnology for Bioanalysis and Cancer Therapeutics

Z Huang, D Wang, Q Zhang, Y Zhang… - Accounts of Materials …, 2024 - ACS Publications
Conspectus Aptamers are single-stranded DNA or RNA molecules composed of 15–80
nucleotides, obtained from a random oligonucleotide library via the systematic evolution of …

Photodynamic O2 Economizer Encapsulated with DNAzyme for Enhancing Mitochondrial Gene‐Photodynamic Therapy

K Zhong, Z Zhang, W Cheng, G Liu… - Advanced …, 2024 - Wiley Online Library
Emerging research suggests that mitochondrial DNA is a potential target for cancer
treatment. However, achieving precise delivery of deoxyribozymes (DNAzymes) and …

Spatially Localized Entropy-Driven Evolution of Nucleic Acid-Based Constitutional Dynamic Networks for Intracellular Imaging and Spatiotemporal Programmable …

N Lin, Y Ouyang, Y Qin, O Karmi, YS Sohn… - Journal of the …, 2024 - ACS Publications
The primer-guided entropy-driven high-throughput evolution of the DNA-based
constitutional dynamic network, CDN, is introduced. The entropy gain associated with the …

Functional Nucleic Acid Probes Based on Two-Photon for Biosensing

K Wu, C Ma, Y Wang - Biosensors, 2023 - mdpi.com
Functional nucleic acid (FNA) probes have been widely used in environmental monitoring,
food analysis, clinical diagnosis, and biological imaging because of their easy synthesis …