Multifaceted nanolipidic carriers: a modish stratagem accentuating nose-to-brain drug delivery

S Shah, AA Patel, BG Prajapati, A Alexander… - Journal of Nanoparticle …, 2023 - Springer
The exponential growth of nanotechnology has focused on therapeutic pursuits, notably for
brain disorders. Nanocarriers have submicron particle sizes, typically around 500 nm. Over …

[HTML][HTML] An overview of nanostructured lipid carriers and its application in drug delivery through different routes

S Khan, A Sharma, V Jain - Advanced Pharmaceutical Bulletin, 2023 - ncbi.nlm.nih.gov
Abstract Nanostructured Lipid Carriers (NLC) are nano-sized colloidal drug delivery system
that contains a lipid mixture consisting of both solid and liquid lipids in their core. This Lipid …

Gastric ulcer healing by chebulinic acid solid dispersion-loaded gastroretentive raft systems: preclinical evidence

P Negi, S Gautam, A Sharma, C Rathore… - Therapeutic …, 2022 - Taylor & Francis
Background: Chebulinic acid (CA), a component in Terminalia chebula, exhibits antiulcer
activity, but has poor aqueous solubility. Raft-forming systems incorporating solid …

Applications of innovative technologies to the delivery of antipsychotics

MC Bergonzi, AR Bilia, E Landucci - Drug Discovery Today, 2022 - Elsevier
Psychosis is a high-incidence pathology associated with a profound alteration in the
perception of reality. The limitations of drugs available on the market have stimulated the …

Nanostructured Lipid Carriers (NLCs) as Effective Drug Delivery Systems: Methods of Preparation and their Therapeutic Applications

HM Alatawi, SS Alhwiti, KA Alsharif… - Recent Patents on …, 2024 - ingentaconnect.com
One of the drug delivery technologies is nanostructured lipid carriers (NLCs), which improve
drug permeability and thus bioavailability. NLCs are nanoparticles made from a lipid matrix …

Synthesis Folate-linked Chitosan-coated Quetiapine/BSA Nano-Carriers as the Efficient Targeted Anti-Cancer Drug Delivery System

HNG Al-Hasnawi, V Pouresmaeil… - Molecular …, 2023 - Springer
Quetiapine (QTP) has been known to suppress cancer progression in patients suffering from
mental disorders. This study aimed to produce the folate-linked chitosan-coated …

Compounded nonsterile preparations and FDA-approved commercially available liquid products for children: A North American update

RH Parrish, LD Ashworth, R Löbenberg, S Benavides… - Pharmaceutics, 2022 - mdpi.com
The purpose of this work was to evaluate the suitability of recent US Food and Drug
Administration (US-FDA)-approved and marketed oral liquid, powder, or granule products …

[HTML][HTML] Self-emulsifying drug delivery system for improved dissolution and oral absorption of quetiapine fumarate: investigation of drug release mechanism and in …

OBH Ayed, MA Lassoued, B Bahloul… - Iranian Journal of …, 2021 - ncbi.nlm.nih.gov
In this study, we focused on quetiapine fumarate (QTF), a class II BCS drug. QTF is an
atypical antipsychotic used in the treatment of schizophrenia and bipolar disorders. Our …

[HTML][HTML] Quality-by-Design-Driven Nanostructured Lipid Scaffold of Apixaban: Optimization, Characterization, and Pharmacokinetic Evaluation

K Patil, N Gujarathi, C Sharma, S Ojha, S Goyal… - Pharmaceutics, 2024 - mdpi.com
Apixaban, an anticoagulant, is limited in its efficacy due to poor solubility, low bioavailability,
and extensive metabolism. This study investigates the application of nanostructured lipid …

Development and evaluation of ketoprofen loaded floating microspheres for sustained delivery

S Agarwal, A Thakur, A Sharma - Materials Today: Proceedings, 2022 - Elsevier
Present study was designed with the objective of formulating floating microspheres of
ketoprofen for sustaining the drug release. Ketoprofen is a cyclooxygenase inhibitor widely …