Overcoming skin barriers through advanced transdermal drug delivery approaches

V Phatale, KK Vaiphei, S Jha, D Patil, M Agrawal… - Journal of controlled …, 2022 - Elsevier
Upon exhaustive research, the transdermal drug delivery system (TDDS) has appeared as a
potential, well-accepted, and popular approach to a novel drug delivery system. Ease of …

[HTML][HTML] Transfersomes: A promising nanoencapsulation technique for transdermal drug delivery

SAT Opatha, V Titapiwatanakun, R Chutoprapat - Pharmaceutics, 2020 - mdpi.com
Transdermal delivery systems have gained much interest in recent years owing to their
advantages compared to conventional oral and parenteral delivery systems. They are …

Current advances in lipid nanosystems intended for topical and transdermal drug delivery applications

N Akombaetwa, AB Ilangala, L Thom, PB Memvanga… - Pharmaceutics, 2023 - mdpi.com
Skin delivery is an exciting and challenging field. It is a promising approach for effective drug
delivery due to its ease of administration, ease of handling, high flexibility, controlled …

[HTML][HTML] Transfersomes: a revolutionary nanosystem for efficient transdermal drug delivery

MW Akram, H Jamshaid, FU Rehman, M Zaeem… - AAPS …, 2022 - Springer
Transdermal delivery system has gained significance in drug delivery owing to its
advantages over the conventional delivery systems. However, the barriers of stratum …

Development of stable nano-sized transfersomes as a rectal colloid for enhanced delivery of cannabidiol

T Moqejwa, T Marimuthu, PPD Kondiah, YE Choonara - Pharmaceutics, 2022 - mdpi.com
Current cannabidiol (CBD) formulations are challenged with unpredictable release and
absorption. Rational design of a rectal colloid delivery system can provide a practical …

Investigating the targeting power to brain tissues of intranasal rasagiline mesylate-loaded transferosomal in situ gel for efficient treatment of Parkinson's disease

HN ElShagea, RR Makar, AH Salama, NA Elkasabgy… - Pharmaceutics, 2023 - mdpi.com
Rasagiline mesylate (RSM) is a hydrophilic drug with poor oral bioavailability (36%)
because of hepatic first-pass metabolism. The present study focuses on delivering RSM …

Lipid-based nanovesicular drug delivery systems

T Limongi, F Susa, M Marini, M Allione, B Torre… - Nanomaterials, 2021 - mdpi.com
In designing a new drug, considering the preferred route of administration, various
requirements must be fulfilled. Active molecules pharmacokinetics should be reliable with a …

Skin penetration/permeation success determinants of nanocarriers: Pursuit of a perfect formulation

M Elmowafy - Colloids and Surfaces B: Biointerfaces, 2021 - Elsevier
The advent of nanocarriers in the field of pharmaceutical drug delivery, while exhibiting
considerable advantages, has created challenges for researchers. Among the applications …

Self-assembling drug formulations with tunable permeability and biodegradability

G Gaynanova, L Vasileva, R Kashapov, D Kuznetsova… - Molecules, 2021 - mdpi.com
This review focuses on key topics in the field of drug delivery related to the design of
nanocarriers answering the biomedicine criteria, including biocompatibility, biodegradability …

A comprehensive review on transethosomes as a novel vesicular approach for drug delivery through transdermal route

M Munir, M Zaman, MA Waqar… - Journal of Liposome …, 2024 - Taylor & Francis
Drug delivery through transdermal route is one of the effective methods for the application of
drugs. It overcomes many drawbacks which are encountered with the oral route. Moreover …