Targeting the NLRP3 inflammasome in cardiovascular diseases

S Toldo, E Mezzaroma, LF Buckley, N Potere… - Pharmacology & …, 2022 - Elsevier
The NACHT, leucine-rich repeat (LRR), and pyrin domain (PYD)-containing protein 3
(NLRP3) inflammasome is an intracellular sensing protein complex that plays a major role in …

[HTML][HTML] Neutrophil: a cell with many roles in inflammation or several cell types?

C Rosales - Frontiers in physiology, 2018 - frontiersin.org
Neutrophils are the most abundant leukocytes in the circulation, and have been regarded as
first line of defense in the innate arm of the immune system. They capture and destroy …

[HTML][HTML] Venous thromboembolism in cancer patients: ESMO Clinical Practice Guideline

A Falanga, C Ay, M Di Nisio, G Gerotziafas… - Annals of …, 2023 - Elsevier
Thromboembolism in people with cancer still remains a major health problem and is a
leading cause of mortality after cancer itself, despite being a largely preventable disease. 1 …

Deep vein thrombosis in hospitalized patients with COVID-19 in Wuhan, China: prevalence, risk factors, and outcome

L Zhang, X Feng, D Zhang, C Jiang, H Mei, J Wang… - Circulation, 2020 - Am Heart Assoc
Background: To investigate deep vein thrombosis (DVT) in hospitalized patients with
coronavirus disease 2019 (COVID-19), we performed a single institutional study to evaluate …

Routine venous thromboembolism prophylaxis may be inadequate in the hypercoagulable state of severe coronavirus disease 2019

TK Maatman, F Jalali, C Feizpour… - Critical care …, 2020 - journals.lww.com
Objectives: The aim of this study was to determine the frequency of venous
thromboembolism in critically ill coronavirus disease 2019 patients and associate a degree …

Cardiovascular risk factors associated with venous thromboembolism

J Gregson, S Kaptoge, T Bolton, L Pennells… - JAMA …, 2019 - jamanetwork.com
Importance It is uncertain to what extent established cardiovascular risk factors are
associated with venous thromboembolism (VTE). Objective To estimate the associations of …

[PDF][PDF] Single‐cell transcriptomic analysis reveals a hepatic stellate cell–activation roadmap and myofibroblast origin during liver fibrosis in mice

WU Yang, H He, T Wang, N Su, F Zhang, K Jiang… - …, 2021 - Wiley Online Library
Background and Aims HSCs and portal fibroblasts (PFs) are the major sources of collagen‐
producing myofibroblasts during liver fibrosis, depending on different etiologies. However …

[HTML][HTML] Imaging of acute pulmonary embolism: an update

AJE Moore, J Wachsmann, MR Chamarthy… - Cardiovascular …, 2018 - ncbi.nlm.nih.gov
Imaging plays an important role in the evaluation and management of acute pulmonary
embolism (PE). Computed tomography (CT) pulmonary angiography (CTPA) is the current …

Swarming magnetic nanorobots bio-interfaced by heparinoid-polymer brushes for in vivo safe synergistic thrombolysis

M Yang, Y Zhang, F Mou, C Cao, L Yu, Z Li… - Science Advances, 2023 - science.org
Biocompatible swarming magnetic nanorobots that work in blood vessels for safe and
efficient targeted thrombolytic therapy in vivo are demonstrated. This is achieved by using …

SARS-2 Coronavirus–Associated Hemostatic Lung Abnormality in COVID-19: Is It Pulmonary Thrombosis or Pulmonary Embolism?

J Thachil, A Srivastava - Seminars in thrombosis and …, 2020 - thieme-connect.com
The coronavirus disease 2019 (COVID-19) pandemic has claimed several thousand lives
since the first case was described in Wuhan, China, in December 2019. 1 This has mainly …