Importance More than 42 000 Americans died of opioid overdoses in 2016, and the fatalities
continue to increase. This review analyzes the factors that triggered the opioid crisis and its …

Psychoactive substances with chemical structures or pharmacological profiles that are
similar to traditional drugs of abuse continue to emerge on the recreational drug market …

From 2013 to 2019, the age-adjusted rate of deaths involving synthetic opioids other than
methadone increased 1,040%, and for psychostimulants increased 317%. During 2018 …

Abstract Drawing from the National Survey on Drug Use and Health (NSDUH; N= 611,880),
a nationally representative survey of US adolescents and adults, we assess age, period, and …

HCV infection, risk-based screening failed to identify the majority of individuals with HCV
infection due to both clinician and patient barriers.(9-12) Analysis of the 2003-2010 National …

In 2017, among 70,237 drug overdose deaths, 47,600 (67.8%) involved opioids, with
increases across age groups, racial/ethnic groups, county urbanization levels, and in …

From 2016 to 2017, death rates involving cocaine and psychostimulants increased across
age groups, racial/ethnic groups, county urbanization levels, and multiple states. Death rates …

INTRODUCTION The epidemic of substance use disorders and drug overdose deaths is a
growing public health crisis in the United States. Every day, 174 people die from drug …

Deaths from drug overdose continue to contribute to overall mortality and the lowering of life
expectancy in the United States (1-4). This report uses the most recent data from the …

Alcohol use disorder is a major contributor to the morbidity and mortality burden worldwide.
It often coexists with other psychiatric disorders; however, the nature of this comorbidity is …