Background: In vitro toxicology studies of tobacco and tobacco smoke have been used to
understand why tobacco use causes cancer and to assess the toxicologic impact of tobacco …

RSV is one of the major infectious agents in paediatrics, and its relationship with air pollution
is frequently observed. However, the molecular basis of this interaction is sparsely reported …

While cigarette smoking is prevalent amongst HIV-infected patients, the effects of cigarette
smoke constituents in cells of myeloid lineage are poorly known. Recently, we have shown …

Respiratory syncytial viral (RSV) infections are a frequent cause of chronic obstructive
pulmonary disease (COPD) exacerbations, which are a major factor in disease progression …

Background Although individuals exposed to cigarette smoke are more susceptible to
respiratory infection, the effects of cigarette smoke on lung defense are incompletely …

Exposure to environmental tobacco smoke (ETS) is a known risk factor for the development
of chronic lung diseases, cancer, and the exacerbation of viral infections. Extracellular …

Chronic obstructive pulmonary disease (COPD) is the third leading cause of mortality in the
United States. The major cause of COPD is cigarette smoking. Extensive leukocyte influx …

Smokers are more susceptible to respiratory viral infections, including influenza virus, but
the mechanisms mediating this effect are unknown. To determine how epithelial cells …

Human rhinovirus (HRV) infections are associated with exacerbations of lower-airway
diseases. HRV-induced production of proinflammatory chemokines, such as CXCL10, from …

Although individuals exposed to cigarette smoke are more susceptible to respiratory
infection, the effects of cigarette smoke on pulmonary defense are incompletely understood …