Key Clinical Points Obstructive Sleep Apnea in Adults Obstructive sleep apnea is common
and is an independent risk factor for motor vehicle accidents and cardiovascular disease …

The key regulators of the transcriptional response to hypoxia and inflammation (hypoxia
inducible factor, HIF, and nuclear factor-kappa B, NF-κB, respectively) are evolutionarily …

Nonalcoholic fatty liver disease (NAFLD) is a spectrum of disease, extending from simple
steatosis to inflammation and fibrosis with a significant risk for the development of cirrhosis. It …

Background Obesity and obstructive sleep apnea tend to coexist and are associated with
inflammation, insulin resistance, dyslipidemia, and high blood pressure, but their causal …

Sleep duration has been linked to obesity and there is also an emerging literature in animals
demonstrating a relationship between the timing of feeding and weight regulation. However …

Recent studies have demonstrated that obstructive sleep apnea (OSA) is associated with the
development and evolution of nonalcoholic fatty liver disease (NAFLD), independent of …

The importance of sleep to hormones and glucose metabolism was first documented more
than four decades ago. Since then, sleep curtailment has become an endemic behavior in …

Executive summary Elevated blood pressure is the strongest modifiable risk factor for
cardiovascular disease worldwide. Despite extensive knowledge about ways to prevent as …

Guidelines are presented for the organisational and clinical peri‐operative management of
anaesthesia and surgery for patients who are obese, along with a summary of the problems …

Rationale: Despite emerging evidence that obstructive sleep apnea (OSA) may cause
metabolic disturbances independently of other known risk factors, it remains unclear …