Placebo and nocebo effects

L Colloca, AJ Barsky - New England Journal of Medicine, 2020 - Mass Medical Soc
Placebo and Nocebo Effects Placebo and nocebo effects (effects of patients' positive and
negative expectations) are powerful and pervasive in clinical practice. Neurobiologic …

The placebo effect: from concepts to genes

B Colagiuri, LA Schenk, MD Kessler, SG Dorsey… - Neuroscience, 2015 - Elsevier
Despite its initial treatment as a nuisance variable, the placebo effect is now recognized as a
powerful determinant of health across many different diseases and encounters. This is in …

[PDF][PDF] Placebo effects in medicine

TJ Kaptchuk, FG Miller - N Engl J Med, 2015 - programinplacebostudies.org
Placebo effects are often considered the effects of an “inert substance,” but that
characterization is misleading. In a broad sense, placebo effects are improvements in …

Are the current guidelines on caffeine use in sport optimal for everyone? Inter-individual variation in caffeine ergogenicity, and a move towards personalised sports …

C Pickering, J Kiely - Sports Medicine, 2018 - Springer
Caffeine use is widespread in sport, with a strong evidence base demonstrating its
ergogenic effect. Based on existing research, current guidelines recommend ingestion of 3 …

Brain connectivity predicts placebo response across chronic pain clinical trials

P Tétreault, A Mansour, E Vachon-Presseau… - PLoS …, 2016 - journals.plos.org
Placebo response in the clinical trial setting is poorly understood and alleged to be driven by
statistical confounds, and its biological underpinnings are questioned. Here we identified …

Open-label placebo: reflections on a research agenda

TJ Kaptchuk - Perspectives in biology and medicine, 2018 - muse.jhu.edu
Open-label placebos (OLP)—placebo pills honestly prescribed—have challenged the notion
that placebos require either deception or concealment to evoke salubrious benefits. This …

Placebo 2.0: the impact of expectations on analgesic treatment outcome

U Bingel - Pain, 2020 - journals.lww.com
Experimental and clinical evidence from the past decades indicates that patients'
expectations about treatment benefits are crucial modulators of health and treatment …

Open label placebo: can honestly prescribed placebos evoke meaningful therapeutic benefits?

TJ Kaptchuk, FG Miller - Bmj, 2018 - bmj.com
Open label placebo: can honestly prescribed placebos evoke meaningful therapeutic benefits? |
The BMJ Skip to main content Intended for healthcare professionals Access provided by Google …

[HTML][HTML] Pain, placebo, and test of treatment efficacy: a narrative review

L Vase, K Wartolowska - British journal of anaesthesia, 2019 - Elsevier
Over the past decade, the mechanisms underlying placebo effects have begun to be
identified. At the same time, the placebo response appears to have increased in …

Increasing uncertainty in CNS clinical trials: the role of placebo, nocebo, and Hawthorne effects

F Benedetti, E Carlino, A Piedimonte - The Lancet Neurology, 2016 - thelancet.com
As modern research continues to unravel the details of the placebo phenomenon in CNS
disorders, uncertainty about therapeutic outcomes in trials of treatments for several …