Emerging evidence suggests that ferroptosis, a unique regulated cell death modality that is
morphologically and mechanistically different from other forms of cell death, plays a vital role …

Hemorrhagic stroke is a devastating cerebrovascular disease with high morbidity and
mortality, for which effective therapies are currently unavailable. Based on different bleeding …

Abstract Background: Menaquinone-4 (MK-4), the isoform of vitamin K2 in the brain, exerts
neuroprotective effects against a variety of central nervous system disorders. This study …

Aims Ischemic stroke is a severe cerebrovascular disease in which neuronal death
continually occurs through multiple forms, including apoptosis, autophagy, pyroptosis and …

Acute lung injury (ALI) is a common critical disease of the respiratory system that progresses
into acute respiratory distress syndrome (ARDS), with high mortality, mainly related to …

Ischemic stroke refers to the sudden loss of blood flow in a specific area of the brain. It is the
fifth leading cause of mortality and the leading cause of permanent disability. The …

Background Ferroptosis is an important therapeutic target to alleviate early brain injury (EBI)
after subarachnoid hemorrhage (SAH), yet the mechanism of neuronal ferroptosis after SAH …

Background Ferroptosis is a type of cell death caused by excessive iron-induced
peroxidation. It has been found to be involved in a variety of diseases, and natural products …

Ferroptosis is a distinct peroxidation-driven form of cell death tightly involved in
subarachnoid hemorrhage (SAH). This study delved into the mechanism of deferoxamine …

Subarachnoid hemorrhage (SAH) is primarily attributed to the rupture of intracranial
aneurysms and is associated with a high incidence of disability and mortality. SAH disrupts …