All classes of drug that are prescribed to treat depression are associated with withdrawal
syndromes. SSRI withdrawal syndrome occurs often and can be severe, and might compel …

Depression in bipolar disorder (BD) patients presents major clinical challenges. As the
predominant psychopathology even in treated BD, depression is associated not only with …

Yatham LN, Kennedy SH, Parikh SV, Schaffer A, Beaulieu S, Alda M, O'Donovan C,
MacQueen G, McIntyre RS, Sharma V, Ravindran A, Young LT, Milev R, Bond DJ, Frey BN …

A revision of the 2008 British Association for Psychopharmacology evidence-based
guidelines for treating depressive disorders with antidepressants was undertaken in order to …

Background: Findings of substantial remaining morbidity in treated major depressive
disorder (MDD) led us to review controlled trials of treatments aimed at preventing early …

Objective: The risks of major affective episodes during pregnancy and during the postpartum
period have rarely been compared in large samples across diagnoses. The authors …

Objective: Rapid eye movement sleep behavior disorder (RBD) is associated with
neurodegenerative disease and particularly with the synucleinopathies. Convenience …

Variants in KCNT1, encoding a sodium-gated potassium channel (subfamily T member 1),
have been associated with a spectrum of epilepsies and neurodevelopmental disorders …

The aim of this article is to discuss the validity of relapse prevention trials and the issue of
withdrawal confounding in these trials. Recommendations for long-term antidepressant …

Strong evidence supports the existence of a discontinuation syndrome following the
withdrawal of antidepressant medication, particularly second-generation antidepressants …