Computational psychiatry needs time and context
Why has computational psychiatry yet to influence routine clinical practice? One reason may
be that it has neglected context and temporal dynamics in the models of certain mental …
be that it has neglected context and temporal dynamics in the models of certain mental …
Smartphones and the neuroscience of mental health
CM Gillan, RB Rutledge - Annual Review of Neuroscience, 2021 - annualreviews.org
Improvements in understanding the neurobiological basis of mental illness have
unfortunately not translated into major advances in treatment. At this point, it is clear that …
unfortunately not translated into major advances in treatment. At this point, it is clear that …
Computational models of subjective feelings in psychiatry
Research in computational psychiatry is dominated by models of behavior. Subjective
experience during behavioral tasks is not well understood, even though it should be relevant …
experience during behavioral tasks is not well understood, even though it should be relevant …
[HTML][HTML] The miRNome of depression
Depression is an effect of complex interactions between genetic, epigenetic and
environmental factors. It is well established that stress responses are associated with …
environmental factors. It is well established that stress responses are associated with …
A neurobiological perspective on social influence: Serotonin and social adaptation
P Duerler, FX Vollenweider… - Journal of …, 2022 - Wiley Online Library
Humans are inherently social beings. Being suggestible to each other's expectations
enables pro‐social skills that are crucial for social learning and adaptation. Despite their …
enables pro‐social skills that are crucial for social learning and adaptation. Despite their …
[HTML][HTML] Serotonin modulates asymmetric learning from reward and punishment in healthy human volunteers
Instrumental learning is driven by a history of outcome success and failure. Here, we
examined the impact of serotonin on learning from positive and negative outcomes. Healthy …
examined the impact of serotonin on learning from positive and negative outcomes. Healthy …
Psychological mechanisms and functions of 5-HT and SSRIs in potential therapeutic change: Lessons from the serotonergic modulation of action selection, learning …
Uncertainty regarding which psychological mechanisms are fundamental in mediating SSRI
treatment outcomes and wide-ranging variability in their efficacy has raised more questions …
treatment outcomes and wide-ranging variability in their efficacy has raised more questions …
Loss of control over eating: A systematic review of task based research into impulsive and compulsive processes in binge eating
M Waltmann, N Herzog, A Horstmann… - … & Biobehavioral Reviews, 2021 - Elsevier
Recurring episodes of excessive food intake in binge eating disorder can be understood
through the lens of behavioral control systems: patients repeat maladaptive behaviors …
through the lens of behavioral control systems: patients repeat maladaptive behaviors …
[HTML][HTML] Effects of escitalopram on synaptic density in the healthy human brain: a randomized controlled trial
Selective serotonin reuptake inhibitors (SSRIs) are widely used for treating neuropsychiatric
disorders. However, the exact mechanism of action and why effects can take several weeks …
disorders. However, the exact mechanism of action and why effects can take several weeks …