Computational psychiatry needs time and context

PF Hitchcock, EI Fried, MJ Frank - Annual review of psychology, 2022 - annualreviews.org
Why has computational psychiatry yet to influence routine clinical practice? One reason may
be that it has neglected context and temporal dynamics in the models of certain mental …

Smartphones and the neuroscience of mental health

CM Gillan, RB Rutledge - Annual Review of Neuroscience, 2021 - annualreviews.org
Improvements in understanding the neurobiological basis of mental illness have
unfortunately not translated into major advances in treatment. At this point, it is clear that …

Emotions as computations

A Emanuel, E Eldar - Neuroscience & Biobehavioral Reviews, 2023 - Elsevier
Emotions ubiquitously impact action, learning, and perception, yet their essence and role
remain widely debated. Computational accounts of emotion aspire to answer these …

Computational models of subjective feelings in psychiatry

CH Kao, GW Feng, JK Hur, H Jarvis… - … & Biobehavioral Reviews, 2023 - Elsevier
Research in computational psychiatry is dominated by models of behavior. Subjective
experience during behavioral tasks is not well understood, even though it should be relevant …

[HTML][HTML] The miRNome of depression

D Żurawek, G Turecki - International Journal of Molecular Sciences, 2021 - mdpi.com
Depression is an effect of complex interactions between genetic, epigenetic and
environmental factors. It is well established that stress responses are associated with …

A neurobiological perspective on social influence: Serotonin and social adaptation

P Duerler, FX Vollenweider… - Journal of …, 2022 - Wiley Online Library
Humans are inherently social beings. Being suggestible to each other's expectations
enables pro‐social skills that are crucial for social learning and adaptation. Despite their …

[HTML][HTML] Serotonin modulates asymmetric learning from reward and punishment in healthy human volunteers

J Michely, E Eldar, A Erdman, IM Martin… - Communications …, 2022 - nature.com
Instrumental learning is driven by a history of outcome success and failure. Here, we
examined the impact of serotonin on learning from positive and negative outcomes. Healthy …

Psychological mechanisms and functions of 5-HT and SSRIs in potential therapeutic change: Lessons from the serotonergic modulation of action selection, learning …

C Roberts, BJ Sahakian, TW Robbins - Neuroscience & biobehavioral …, 2020 - Elsevier
Uncertainty regarding which psychological mechanisms are fundamental in mediating SSRI
treatment outcomes and wide-ranging variability in their efficacy has raised more questions …

Loss of control over eating: A systematic review of task based research into impulsive and compulsive processes in binge eating

M Waltmann, N Herzog, A Horstmann… - … & Biobehavioral Reviews, 2021 - Elsevier
Recurring episodes of excessive food intake in binge eating disorder can be understood
through the lens of behavioral control systems: patients repeat maladaptive behaviors …

[HTML][HTML] Effects of escitalopram on synaptic density in the healthy human brain: a randomized controlled trial

A Johansen, S Armand, P Plavén-Sigray… - Molecular …, 2023 - nature.com
Selective serotonin reuptake inhibitors (SSRIs) are widely used for treating neuropsychiatric
disorders. However, the exact mechanism of action and why effects can take several weeks …