When all glasses look half empty: a computational model of reference dependent evaluation to explain depression

F Rigoli - Journal of Cognitive Psychology, 2022 - Taylor & Francis
Computational proposals argue that impairments in evaluation are central to depression. At
the same time, contemporary theories of evaluation highlight its reference dependent nature …

Reinforcement learning modeling reveals a reward-history-dependent strategy underlying reversal learning in squirrel monkeys.

BA Bari, MJ Moerke, HP Jedema… - Behavioral …, 2022 - psycnet.apa.org
Insight into psychiatric disease and development of therapeutics relies on behavioral tasks
that study similar cognitive constructs in multiple species. The reversal learning task is one …

[HTML][HTML] Misperceiving momentum: computational mechanisms of biased striatal reward prediction errors in bipolar disorder

H Moningka, L Mason - Biological Psychiatry Global Open Science, 2024 - Elsevier
Background Dysregulated reward processing and mood instability are core features of
bipolar disorder that have largely been considered separately, with contradictory findings …

The half-empty/full glass in mental health: A reference-dependent computational model of evaluation in psychopathology

F Rigoli, C Martinelli, G Pezzulo - Clinical Psychological …, 2021 - journals.sagepub.com
Evaluation (the process attributing value to outcomes) underlies “hot” aspects of cognition,
such as emotion, affect, and motivation. In several psychopathologies, such as depression …

1H Nuclear Magnetic Resonance: A Future Approach to the Metabolic Profiling of Psychedelics in Human Biofluids?

S Vilca-Melendez, MV Uthaug, JL Griffin - Frontiers in Psychiatry, 2021 - frontiersin.org
While psychedelics may have therapeutic potential for treating mental health disorders such
as depression, further research is needed to better understand their biological effects and …

The selective serotonin reuptake inhibitor sertraline alters learning from aversive reinforcements in patients with depression: evidence from a randomized controlled …

J Malamud, G Lewis, M Moutoussis, L Duffy… - Psychological …, 2024 - cambridge.org
BackgroundSelective serotonin reuptake inhibitors (SSRIs) are first-line pharmacological
treatments for depression and anxiety. However, little is known about how pharmacological …

Hierarchical TiO2–Ag/hydrogel coating used for outstanding antifouling detection of serotonin

X He, S Ma, N Sun, M Hou, Z Tan, R Cao - Macromolecular Research, 2024 - Springer
Abstract Serotonin (5-HT) is an important neurotransmitter in vivo, regulating almost all
human behavior and cognitive processes. Antifouling surface that can prevent undesirable …

Mood computational mechanisms underlying increased risk behavior in adolescent suicidal patients

Z Wang, T Nan, T Wang, Y Liu, F Lu, Y Yu, X Cai, Z He… - medRxiv, 2023 - medrxiv.org
Suicidal thoughts and behaviors (STB) are one of leading causes of death worldwide.
Although literature has consistently reported increased risk behavior in patients with STB …

Escitalopram increases synaptic density in the human brain over weeks: A randomized controlled trial

A Johansen, S Armand, P Plavén-Sigray, A Nasser… - 2023 - researchsquare.com
Selective serotonin reuptake inhibitors (SSRIs) are widely used for treating neuropsychiatric
disorders. However, the exact mechanism of action and why effects can take several weeks …

Hope for brain health: impacting the life course and society

J Dasgupta, JA Furlano, Z Bandler, S Fittipaldi… - Frontiers in …, 2023 - frontiersin.org
Hope is a cognitive process by which an individual can identify their personal goals and
develop actionable steps to achieve results. It has the potential to positively impact people's …