Chagas disease in the United States: a public health approach
Trypanosoma cruzi is the etiological agent of Chagas disease, usually transmitted by
triatomine vectors. An estimated 20 to 30% of infected individuals develop potentially lethal …
triatomine vectors. An estimated 20 to 30% of infected individuals develop potentially lethal …
Trypanosoma cruzi genetic diversity: Something new for something known about Chagas disease manifestations, serodiagnosis and drug sensitivity
B Zingales - Acta tropica, 2018 - Elsevier
The genetic diversity of Trypanosoma cruzi, the protozoan agent of Chagas disease, is
widely recognized. At present, T. cruzi is partitioned into seven discrete typing units (DTUs) …
widely recognized. At present, T. cruzi is partitioned into seven discrete typing units (DTUs) …
The revised Trypanosoma cruzi subspecific nomenclature: rationale, epidemiological relevance and research applications
B Zingales, MA Miles, DA Campbell… - Infection, genetics and …, 2012 - Elsevier
The protozoan Trypanosoma cruzi, its mammalian reservoirs, and vectors have existed in
nature for millions of years. The human infection, named Chagas disease, is a major public …
nature for millions of years. The human infection, named Chagas disease, is a major public …
Trypanosoma cruzi and Chagas' disease in the United States
C Bern, S Kjos, MJ Yabsley… - Clinical microbiology …, 2011 - Am Soc Microbiol
Chagas' disease is caused by the protozoan parasite Trypanosoma cruzi and causes
potentially life-threatening disease of the heart and gastrointestinal tract. The southern half …
potentially life-threatening disease of the heart and gastrointestinal tract. The southern half …
Socioecological vulnerability and the risk of zoonotic disease emergence in Brazil
In developing countries, outbreaks of zoonotic diseases (ZDs) result from intertwined
ecological, socioeconomic, and demographic processes that shape conditions for (i) …
ecological, socioeconomic, and demographic processes that shape conditions for (i) …
[HTML][HTML] Over Six Thousand Trypanosoma cruzi Strains Classified into Discrete Typing Units (DTUs): Attempt at an Inventory
SF Brenière, E Waleckx, C Barnabé - PLoS neglected tropical …, 2016 - journals.plos.org
Trypanosoma cruzi, the causative agent of Chagas disease, presents wide genetic diversity.
Currently, six discrete typing units (DTUs), named TcI to TcVI, and a seventh one called …
Currently, six discrete typing units (DTUs), named TcI to TcVI, and a seventh one called …
Between a bug and a hard place: Trypanosoma cruzi genetic diversity and the clinical outcomes of Chagas disease
LA Messenger, MA Miles, C Bern - Expert review of anti-infective …, 2015 - Taylor & Francis
Over the last 30 years, concomitant with successful transnational disease control programs
across Latin America, Chagas disease has expanded from a neglected, endemic parasitic …
across Latin America, Chagas disease has expanded from a neglected, endemic parasitic …
Pathogenesis of chagas' disease: parasite persistence and autoimmunity
ARL Teixeira, MM Hecht, MC Guimaro… - Clinical microbiology …, 2011 - Am Soc Microbiol
Acute Trypanosoma cruzi infections can be asymptomatic, but chronically infected
individuals can die of Chagas' disease. The transfer of the parasite mitochondrial kinetoplast …
individuals can die of Chagas' disease. The transfer of the parasite mitochondrial kinetoplast …
Genetic diversity of Trypanosoma cruzi in bats, and multilocus phylogenetic and phylogeographical analyses supporting Tcbat as an independent DTU (discrete …
L Lima, O Espinosa-Álvarez, PA Ortiz, JA Trejo-Varón… - Acta tropica, 2015 - Elsevier
Trypanosoma cruzi is a complex of phenotypically and genetically diverse isolates
distributed in six discrete typing units (DTUs) designated as TcI–TcVI. Five years ago, T …
distributed in six discrete typing units (DTUs) designated as TcI–TcVI. Five years ago, T …
[HTML][HTML] Nitroheterocyclic compounds are more efficacious than CYP51 inhibitors against Trypanosoma cruzi: implications for Chagas disease drug discovery and …
Advocacy for better drugs and access to treatment has boosted the interest in drug discovery
and development for Chagas disease, a chronic infection caused by the genetically …
and development for Chagas disease, a chronic infection caused by the genetically …