Chronic stress-induced depression and anxiety priming modulated by gut-brain-axis immunity

S Westfall, F Caracci, M Estill, T Frolinger… - Frontiers in …, 2021 - frontiersin.org
Chronic stress manifests as depressive-and anxiety-like behavior while recurrent stress
elicits disproportionate behavioral impairments linked to stress-induced immunological …

Roles of the intestinal microbiota in pathogen protection

C Ubeda, A Djukovic, S Isaac - Clinical & translational …, 2017 - Wiley Online Library
Hundreds of commensal bacterial species inhabit the gastrointestinal tract. This diverse
microbial ecosystem plays a crucial role in the prevention and resolution of infectious …

Diverse developmental pathways of intestinal intraepithelial lymphocytes

BD McDonald, B Jabri, A Bendelac - Nature Reviews Immunology, 2018 - nature.com
The intestinal epithelial barrier is patrolled by resident intraepithelial lymphocytes (IELs) that
are involved in host defence against pathogens, wound repair and homeostatic interactions …

Functional and phenotypic heterogeneity of group 3 innate lymphoid cells

F Melo‐Gonzalez, MR Hepworth - Immunology, 2017 - Wiley Online Library
Group 3 innate lymphoid cells (ILC 3), defined by expression of the transcription factor
retinoid‐related orphan receptor γt, play key roles in the regulation of inflammation and …

Transdifferentiation of tumor infiltrating innate lymphoid cells during progression of colorectal cancer

S Wang, Y Qu, P Xia, Y Chen, X Zhu, J Zhang, G Wang… - Cell research, 2020 - nature.com
Innate lymphoid cells (ILCs) reside in mucosal surfaces to potentiate immune responses,
sustain mucosal integrity and maintain tissue homeostasis. However, how tumor infiltrating …

Dietary fiber-induced microbial short chain fatty acids suppress ILC2-dependent airway inflammation

G Lewis, B Wang, P Shafiei Jahani, BP Hurrell… - Frontiers in …, 2019 - frontiersin.org
Group 2 Innate lymphoid cells (ILC2) contribute significantly to allergic inflammation.
However, the role of microbiota on ILC2s remains to be unraveled. Here we show that short …

Innate lymphoid cell development: AT cell perspective

DE Cherrier, N Serafini, JP Di Santo - Immunity, 2018 - cell.com
Innate lymphoid cells (ILCs) and natural killer (NK) cells have garnered considerable
interest due to their unique functional properties in immune defense and tissue homeostasis …

Single-cell genomics: a stepping stone for future immunology discoveries

A Giladi, I Amit - Cell, 2018 - cell.com
The immunology field has invested great efforts and ingenuity to characterize the various
immune cell types and elucidate their functions. However, accumulating evidence indicates …

[HTML][HTML] Diabetic gut microbiota dysbiosis as an inflammaging and immunosenescence condition that fosters progression of retinopathy and nephropathy

R Fernandes, SD Viana, S Nunes, F Reis - Biochimica Et Biophysica Acta …, 2019 - Elsevier
The increased prevalence of type 2 diabetes mellitus (T2DM) and life expectancy of diabetic
patients fosters the worldwide prevalence of retinopathy and nephropathy, two major …

[HTML][HTML] The gut ecosystem and immune tolerance

T Shao, R Hsu, DL Rafizadeh, L Wang, CL Bowlus… - Journal of …, 2023 - Elsevier
The gastrointestinal tract is home to the largest microbial population in the human body. The
gut microbiota plays significant roles in the development of the gut immune system and has …