L-Arginine: glycine amidinotransferase (AGAT) catalyzes the formation of L-homoarginine
(hArg) and L-ornithine (Orn) from L-arginine (Arg) and L-lysine (Lys): Arg+ Lys↔ hArg+ Orn; …

Urea transporters have been cloned from kidney medulla (UT-A) and erythrocytes (UT-B).
We determined whether UT-A proteins could be detected in heart and whether their …

Objective: Ornithine decarboxylase (ODC) is an initial rate-limiting enzyme in the synthesis
of polyamines (putrescine, spermidine, and spermine) that play a role in cell growth and …

These studies were designed to determine the consequences of constitutive overexpression
of ornithine decarboxylase (ODC) in the heart. Induction of ODC is known to occur in …

The present study was designed to provide a better understanding of the role played by
AdoMetDC (S-adenosylmethionine decarboxylase), the key rate-controlling enzyme in the …

Two lines of transgenic mice were produced with constitutive expression of antizyme-1 in the
heart, driven from the cardiac α-myosin heavy chain promoter. The use of engineered …

Androgens produce acute vasodilation of systemic, pulmonary, and coronary arteries in
several mammal preparations and increase cardiomyocyte contractility. A decrease of the …

The present study was undertaken to investigate the effect of iron dextran treatment on
polyamine oxidase (PAO) activity, iron accumulation, and lipid peroxidation in livers and …

The role that the induction of cardiac ornithine decarboxylase (ODC), a key enzyme in
polyamine biosynthesis, by beta‐adrenergic agents may have in heart hypertrophy is a …

抄録 It is well known that isoproterenol (ISO) a nonselective β adrenoceptor agonist induces
cardiac hypertrophy. It can be assumed that, in addition to its direct cardiac effect, ISO has a …