[HTML][HTML] Two-sample Mendelian randomization analysis investigates causal associations between gut microbial genera and inflammatory bowel disease, and …

B Liu, D Ye, H Yang, J Song, X Sun, Y Mao… - Frontiers in …, 2022 - frontiersin.org
Background Intestinal dysbiosis is associated with inflammatory bowel disease (IBD).
Ulcerative colitis (UC) and Crohn's disease (CD), two subtypes of IBD, are characterized by …

[HTML][HTML] Effects and mechanisms of natural alkaloids for prevention and treatment of osteoporosis

B Lin, P Xu, J Zheng, X Deng, Q Ye, Z Huang… - Frontiers in …, 2022 - frontiersin.org
Natural alkaloids are polycyclic, nitrogen-containing, and basic compounds obtained from
plants. In this review, the advances in bioactive alkaloids with respect to their chemical …

[HTML][HTML] Causal association between systemic lupus erythematosus and the risk of dementia: A Mendelian randomization study

T Jin, W Huang, F Cao, X Yu, S Guo, Z Ying… - Frontiers in …, 2022 - frontiersin.org
Introduction It is well-documented that systemic lupus erythematosus (SLE) is associated
with dementia. However, the genetic causality of this association remains unclear …

[HTML][HTML] Causal association of sleep disturbances and low back pain: a bidirectional two-sample Mendelian randomization study

G Luo, Y Yao, J Tao, T Wang, M Yan - Frontiers in Neuroscience, 2022 - frontiersin.org
Background Previous observational studies have shown that low back pain (LBP) often
coexists with sleep disturbances, however, the causal relationship remains unclear. In the …

Shared genetics and causality underlying epilepsy and attention-deficit hyperactivity disorder

Y Wu, Y Li, J Zhu, J Long - Psychiatry research, 2022 - Elsevier
The prevalence of attention deficit hyperactivity disorder (ADHD) in patients with epilepsy
was much higher than prevalence in general population, and vice versa. The mechanisms …

[HTML][HTML] Mendelian randomization supports the causal role of fasting glucose on periodontitis

Y Wang, T Chu, Y Gong, S Li, L Wu, L Jin… - Frontiers in …, 2022 - frontiersin.org
Purpose The effect of hyperglycemia on periodontitis is mainly based on observational
studies, and inconsistent results were found whether periodontal treatment favors glycemic …

[HTML][HTML] Causal relationship between gut microbiota and urticaria: a bidirectional two-sample mendelian randomization study

YZ Shi, QF Tao, HY Qin, Y Li, H Zheng - Frontiers in Microbiology, 2023 - frontiersin.org
Background Cumulative evidence showed an association between gut microbiota and
urticaria, but the causal relationship between them is unclear. We aimed to verify whether …

Association between the gut microbiota and nonalcoholic fatty liver disease: a two-sample Mendelian randomization study

Y Li, X Liang, Y Lyu, K Wang, L Han, Y Wang… - Digestive and Liver …, 2023 - Elsevier
Background Increasing studies have shown that there is a significant association between
gut microbiota and non-alcoholic fatty liver disease. Aims To show the potential association …

[HTML][HTML] Dissecting the causal relationship between household income status and genetic susceptibility to cardiovascular-related diseases: insights from bidirectional …

X Zheng, Y Yang, J Chen, B Lu - BMC Public Health, 2023 - Springer
Objectives Observational studies have revealed that socioeconomic status is associated
with cardiovascular health. However, the potential causal effect remains unclear. Hence, we …

Mendelian randomization investigation highlights different roles of selenium status in mental disorders

X Guo, P Tang, C Hou, R Li - Progress in Neuro-Psychopharmacology and …, 2023 - Elsevier
Observational studies have suggested a relationship between selenium status and mental
disorders (MDs). However, it remains unclear whether selenium status was causally …