Network analysis and transcriptome profiling identify autophagic and mitochondrial dysfunctions in SARS-CoV-2 infection

K Singh, YC Chen, S Hassanzadeh, K Han… - Frontiers in …, 2021 - frontiersin.org
Analyzing host cells' transcriptional response to severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) infection will help delineate biological processes underlying …

Electronic-cigarette use alters nasal mucosal immune response to live-attenuated influenza virus. A clinical trial

ME Rebuli, E Glista-Baker, JR Hoffman… - American journal of …, 2021 - atsjournals.org
Inhalation of tobacco smoke has been linked to increased risk of viral infection, such as
influenza. Inhalation of electronic-cigarette (e-cigarette) aerosol has also recently been …

The application of new approach methodologies in respiratory disease research: Their role in improving translational medicine from bench to bedside

ACG da Silva, MC Valadares - Alternatives to Laboratory …, 2023 - journals.sagepub.com
The SARS-CoV-2 outbreak focused global attention on the shortcomings of the drug
discovery process. It led to its acceleration in several areas, particularly in the processes …

[HTML][HTML] Comparison of biological and transcriptomic effects of conventional cigarette and electronic cigarette smoke exposure at toxicological dose in BEAS-2B cells

L Wang, Y Wang, J Chen, XM Yang, XT Jiang… - Ecotoxicology and …, 2021 - Elsevier
Cigarette seriously affects human health, and electronic cigarette (e-cigarette), considered
as cigarette substitutes, become popular as its contribution to quit smoking. But scientific …

Cigarette smoke dampens antiviral signaling in small airway epithelial cells by disrupting TLR3 cleavage

PF Duffney, CE McCarthy, A Nogales… - … of Physiology-Lung …, 2018 - journals.physiology.org
Cigarette smokers and people exposed to second-hand smoke are at an increased risk for
pulmonary viral infections, and yet the mechanism responsible for this heightened …

Cigarette smoking modulation of saliva microbial composition and cytokine levels

M Rodríguez-Rabassa, P López… - International journal of …, 2018 - mdpi.com
Tobacco use has been implicated as an immunomodulator in the oral cavity and contributes
to the development of oral cancer. In the present study, we investigated the effects of …

Bacterial species associated with highly allergenic plant pollen yield a high level of endotoxins and induce chemokine and cytokine release from human A549 cells

B Ambika Manirajan, AK Hinrichs, S Ratering, V Rusch… - Inflammation, 2022 - Springer
Sensitization to pollen allergens has been increasing in Europe every year. Most studies in
this field are related to climate change, phenology, allergens associated with different …

Cerium oxide enhances the toxicity of zinc oxide nanoparticles in human lung epithelial cell cultures

T Al Rashaideh, N Metwali, SS Perry… - Toxics, 2022 - mdpi.com
Recently, many approaches have been developed to improve the performance of
nanomaterials. Combining more than one nanomaterial is one such approach that achieves …

Maresin 1 attenuates pro‐inflammatory activation induced by β‐amyloid and stimulates its uptake

Y Wang, A Leppert, S Tan… - Journal of cellular …, 2021 - Wiley Online Library
Alzheimer's disease (AD) is the most common dementia, characterized by pathological
accumulation of β‐amyloid (Aβ) and hyperphosphorylation of tau protein, together with a …

Cigarette smoke-induced inflammation: NLRP10-mediated mechanisms

G Kaur, P Bagam, R Pinkston, DP Singh, S Batra - Toxicology, 2018 - Elsevier
Chronic obstructive pulmonary disease (COPD) is a progressive, life-threatening disease
that causes irreversible lung damage. Cigarette smoking is the chief etiologic factor for the …